The role of dietary protein and vitamin D in maintaining musculoskeletal health in postmenopausal women: A consensus statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)

被引:192
|
作者
Rizzoli, Rene [1 ,2 ]
Stevenson, John C. [3 ]
Bauer, Juergen M. [4 ]
van Loon, Luc J. C. [5 ]
Walrand, Stephane [6 ,7 ]
Kanis, John A. [8 ]
Cooper, Cyrus [9 ,10 ,11 ]
Brandi, Maria-Luisa [12 ]
Diez-Perez, Adolfo [13 ,14 ]
Reginster, Jean-Yves [15 ,16 ]
机构
[1] Univ Hosp Geneva, Div Bone Dis, CH-1211 Geneva 14, Switzerland
[2] Fac Med, CH-1211 Geneva 14, Switzerland
[3] Univ London Imperial Coll Sci Technol & Med, Royal Brompton & Harefield NHS Fdn Trust, Natl Heart & Lung Inst, London SW3 6NP, England
[4] Carl von Ossietzky Univ Oldenburg, Dept Geriatr Med, D-26129 Oldenburg, Germany
[5] Maastricht Univ, NUTRIM Sch Nutr Toxicol & Metab, NL-6200 MD Maastricht, Netherlands
[6] Univ Auvergne, INRA, F-63001 Clermont Ferrand 1, France
[7] Univ Auvergne, Clermont Univ, F-63001 Clermont Ferrand 1, France
[8] Univ Sheffield, Ctr Metab Bone Dis, Sheffield S10 2RX, S Yorkshire, England
[9] Univ Southampton, Southampton Gen Hosp, MRC Lifecourse Epidemiol Unit, Southampton SO16 6YD, Hants, England
[10] Univ Southampton, Southampton Gen Hosp, NIHR Nutr Biomed Res Ctr, Southampton SO16 6YD, Hants, England
[11] Univ Oxford, NIHR Musculoskeletal Biomed Res Unit, Oxford, England
[12] Univ Florence, Dept Surg & Translat Med, I-50121 Florence, Italy
[13] Autonomous Univ Barcelona, Hosp Mar IMIM, Dept Internal Med, Barcelona, Spain
[14] Inst Carlos III, RETICEF, Barcelona, Spain
[15] Univ Liege, Dept Publ Hlth Sci, Liege, Belgium
[16] Univ Liege, CHU Ctr Ville, Bone & Cartilage Metab Unit, Liege, Belgium
关键词
Musculoskeletal health; Menopause; Osteoporosis; Sarcopenia; Prevention; Physical exercise; HORMONE REPLACEMENT THERAPY; MUSCLE MASS SARCOPENIA; ESSENTIAL AMINO-ACIDS; FRAIL ELDERLY-PEOPLE; BONE-MINERAL DENSITY; SKELETAL-MUSCLE; OLDER-ADULTS; RESISTANCE EXERCISE; PHYSICAL PERFORMANCE; D SUPPLEMENTATION;
D O I
10.1016/j.maturitas.2014.07.005
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
From 50 years of age, postmenopausal women are at an increased risk of developing sarcopenia and osteoporosis as a result of deterioration of musculoskeletal health. Both disorders increase the risk of falls and fractures. The risk of developing sarcopenia and osteoporosis may be attenuated through healthy lifestyle changes, which include adequate dietary protein, calcium and vitamin D intakes, and regular physical activity/exercise, besides hormone replacement therapy when appropriate. Protein intake and physical activity are the main anabolic stimuli for muscle protein synthesis. Exercise training leads to increased muscle mass and strength, and the combination of optimal protein intake and exercise produces a greater degree of muscle protein accretion than either intervention alone. Similarly, adequate dietary protein intake and resistance exercise are important contributors to the maintenance of bone strength. Vitamin D helps to maintain muscle mass and strength as well as bone health. These findings suggest that healthy lifestyle measures in women aged >50 years are essential to allow healthy ageing. The European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) recommends optimal dietary protein intake of 1.0-1.2 g/kg body weight/d with at least 20-25 g of high-quality protein at each main meal, with adequate vitamin D intake at 800 IU/d to maintain serum 25-hydroxyvitamin D levels >50 nmol/L as well as calcium intake of 1000 mg/d, alongside regular physical activity/exercise 3-5 times/week combined with protein intake in close proximity to exercise, in postmenopausal women for prevention of age-related deterioration of musculoskeletal health. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:122 / 132
页数:11
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