The Impact of ADHD on Executive Dysfunctions in Neurofibromatosis Type 1

被引：0
|
作者：
Denkinger, Jana Katharina [1 ]
Heimgaertner, Magdalena [1 ]
Mautner, Victor Felix [2 ]
Lidzba, Karen [1 ]
机构：
[1] Univ Klinikum Tubingen, Klin Kinder & Jugendmed, Abt Neuropadiat, Tubingen, Germany
[2] Univ Krankenhaus Eppendorf, Klin & Poliklin Neurol, Hamburg, Germany
来源：
ZEITSCHRIFT FUR NEUROPSYCHOLOGIE | 2018年 / 29卷 / 02期
关键词：
neurofibromatosis type 1; ADHD; executive functions; DEFICIT-HYPERACTIVITY DISORDER; COGNITIVE DEFICITS; CHILDREN; ATTENTION; PROFILE; RAS;
D O I：
10.1024/1016-264X/a000217
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
In addition to having physical complications, children with neurofibromatosis type 1 (NF1) show a wide spectrum of neuropsychological deficits, mainly executive dysfunctions. Approximately 30 % to 50 % of NF1-patients are also diagnosed with a comorbid attention-deficit/hyperactivity disorder (ADHD). Since executive dysfunctions are a core component in ADHD, this study was conceived to show whether executive dysfunctions are genuinely a problem in NF1 - or just one of an ADHD subgroup. Additionally, we investigated whether executive dysfunctions in NF1 differ from those observed in pure ADHD. According to our findings, NF1-patients without ADHD do not show any executive dysfunctions; however, NF1-patients with ADHD exhibit serious impairments. These results show that executive dysfunctions are not a core deficit of NF1 but rather one of ADHD.
引用
收藏
页码：71 / 78
页数：8
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