Synthesis and pharmacological activity of philanthotoxin-343 analogs: Antagonists of ionotropic glutamate receptors

被引：18
|
作者：
Huang, DW
Jiang, H
Nakanishi, K
Usherwood, PNR
机构：
[1] COLUMBIA UNIV,DEPT CHEM,NEW YORK,NY 10027
[2] UNIV NOTTINGHAM,DEPT LIFE SCI,NOTTINGHAM NG7 2RD,ENGLAND
来源：
TETRAHEDRON | 1997年 / 53卷 / 37期
关键词：
D O I：
10.1016/S0040-4020(97)00801-6
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of two classes of Philanthotoxin-343 analogs is described. Quantitative information on the antagonism of quisqualate-sensitive ionotropic glutamate receptors of insect muscle by these compounds is presented. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码：12391 / 12404
页数：14
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