PX-478 prevents gut inflammation and normalizes the expression of tight junction proteins following ethanol and burn injury

被引:0
|
作者
Morris, N. L. [1 ]
Hammer, A. M. [1 ]
Cannon, A. R. [1 ]
Gagnon, R. [1 ]
Li, X. [1 ]
Choudhry, M. A. [1 ]
机构
[1] Loyola Univ Chicago, Div Hlth Sci, Burn & Shock Trauma Res Inst, Alcohol Res Program,Dept Surg,Integrated Cell Bio, Maywood, IL USA
关键词
D O I
暂无
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
引用
收藏
页码:73 / 74
页数:2
相关论文
共 10 条
  • [1] PX-478 IMPROVES THE RELEASE OF ANTIMICROBIOBIAL PEPTIDES AND REDUCES BACTERIAL DYSBIOSIS IN SMALL INTESTINE FOLLOWING ETHANOL AND BURN INJURY
    Morris, N. L.
    Hammer, A. M.
    Cannon, A. R.
    Gagnon, R. C.
    Kuprys, P. V.
    Li, X.
    Choudhry, M. A.
    ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2017, 41 : 206A - 206A
  • [2] Protective effects of PX478 on gut barrier in a mouse model of ethanol and burn injury
    Morris, Niya L.
    Cannon, Abigail R.
    Li, Xiaoling
    Choudhry, Mashkoor A.
    JOURNAL OF LEUKOCYTE BIOLOGY, 2021, 109 (06) : 1121 - 1130
  • [3] BURN-INDUCED GUT BARRIER INJURY IS ATTENUATED BY PHOSPHODIESTERASE INHIBITION: EFFECTS ON TIGHT JUNCTION STRUCTURAL PROTEINS
    Costantini, Todd W.
    Loomis, William H.
    Putnam, James G.
    Drusinsky, Dana
    Deree, Jessica
    Choi, Sunghyuk
    Wolf, Paul
    Baird, Andrew
    Eliceiri, Brian
    Bansal, Vishal
    Coimbra, Raul
    SHOCK, 2009, 31 (04): : 416 - 422
  • [4] Burn-induced gut barrier injury is attenuated by phosphodiesterase inhibition: Effects on tight junction structural proteins
    Costantini, T. W.
    Loomis, W.
    Deree, J.
    Choi, S. H.
    Putnam, J. G.
    Eliceiri, B. P.
    Baird, A.
    Bansal, V.
    Coimbra, R.
    SHOCK, 2008, 29 : 34 - 34
  • [5] INTERLEUKIN-18 MODULATES INTESTINAL EPITHELIAL TIGHT JUNCTION PROTEINS FOLLOWING ALCOHOL INTOXICATION AND BURN INJURY
    Li, X.
    Akhtar, S.
    Choudhry, M. A.
    ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2009, 33 (06) : 33A - 33A
  • [6] KLF4 alleviates cerebral vascular injury by ameliorating vascular endothelial inflammation and regulating tight junction protein expression following ischemic stroke
    Zhang, Xinyu
    Wang, Lu
    Han, Zhenxiang
    Dong, Jing
    Pang, Defang
    Fu, Yuan
    Li, Longxuan
    JOURNAL OF NEUROINFLAMMATION, 2020, 17 (01)
  • [7] KLF4 alleviates cerebral vascular injury by ameliorating vascular endothelial inflammation and regulating tight junction protein expression following ischemic stroke
    Xinyu Zhang
    Lu Wang
    Zhenxiang Han
    Jing Dong
    Defang Pang
    Yuan Fu
    Longxuan Li
    Journal of Neuroinflammation, 17
  • [8] Inhibition of c-Jun N-terminal kinase prevents blood-brain barrier disruption and normalizes the expression of tight junction proteins clautin-5 and ZO-1 in a rat model of subarachnoid hemorrhage
    Chen, Duo
    Wei, Xiang-tai
    Guan, Jun-hong
    Yuan, Jiang-wei
    Peng, Yu-tao
    Song, Lei
    Liu, Yun-hui
    ACTA NEUROCHIRURGICA, 2012, 154 (08) : 1469 - 1476
  • [9] RETRACTION: Inhibition of c-Jun N-terminal kinase prevents blood-brain barrier disruption and normalizes the expression of tight junction proteins clautin-5 and ZO-1 in a rat model of subarachnoid hemorrhage
    Chen, Duo
    Wei, Xiang-tai
    Guan, Jun-hong
    Yuan, Jiang-wei
    Peng, Yu-tao
    Song, Lei
    Liu, Yun-hui
    ACTA NEUROCHIRURGICA, 2024, 166 (01)
  • [10] Overexpression of netrin-1 increases the expression of tight junction-associated proteins, claudin-5, occludin, and ZO-1, following traumatic brain injury in rats
    Wen, Jianfeng
    Qian, Suokai
    Yang, Qifan
    Deng, Lei
    Mo, Ye
    Yu, Yuefei
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2014, 8 (03) : 881 - 886