In-beam PET imaging for the control of heavy-ion tumour therapy

被引:83
|
作者
Pawelke, J
Enghardt, W
Haberer, T
Hasch, BG
Hinz, R
Kramer, M
Lauckner, K
Sobiella, M
机构
[1] TECH UNIV DRESDEN,KLIN STRAHLENTHERAPIE,D-01307 DRESDEN,GERMANY
[2] GESELL SCHWERIONENFORSCH INST DARMSTADT,D-64220 DARMSTADT,GERMANY
关键词
D O I
10.1109/23.632694
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
A method for the in-situ control of the heavy-ion tumour therapy by means of positron emission tomography is introduced. This method is founded on the measurement of the dynamic spatial distributions of beta(+)-emitters generated by nuclear fragmentation during the irradiation and their relation to the dose. In order to study this relationship and to derive the dose distribution from the measured beta(+)-activity distribution, a framework of model calculations is used. Results of phantom experiments with C-12 ion beams will be presented, demonstrating good agreement between experiment and calculation as well as the possibilities and limits of the PET-technique for treatment plan verification and beam monitoring.
引用
收藏
页码:1492 / 1498
页数:7
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