Bevacizumab (Bev) with or without erlotinib as maintenance therapy, in patients (pts) with metastatic colorectal cancer (mCRC): Exploratory analysis according to KRAS status in the gercor DREAM phase III trial

被引:0
|
作者
Samson, Benoit
Tournigand, Christophe
Scheithauer, Werner
Lledo, Gerard
Viret, Frederic
Andre, Thierry
Ramee, Jean Francois
Tubiana-Mathieu, Nicole
Dauba, Jerome
Dupuis, Olivier
Rinaldi, Yves
Mabro, May
Aucoin, Nathalie
Khalil, Ahmed
Latreille, Jean
Louvet, Christophe
Brusquant, David
Bonnetain, Franck
Chibaudel, Benoist
De Gramont, Aimery
机构
[1] Hop Charles LeMoyne, Quebec City, PQ, Canada
[2] Hop Henri Mondor, F-94010 Creteil, France
[3] Med Univ Vienna, Vienna, Austria
[4] Hop Prive Jean Mermoz, Lyon, France
[5] Inst J Paoli I Calmettes, F-13009 Marseille, France
[6] Hop St Antoine, F-75571 Paris, France
[7] Ctr Catherine Sienne, Nantes, France
[8] CHU Limoges, Limoges, France
[9] Ctr Hosp Layne, Mt De Marsan, France
[10] Clin Victor Hugo, Le Mans, France
[11] Hop Ambroise Pare, Marseille, France
[12] Hop Foch, Suresnes, France
[13] Cite Sante Laval, Laval, PQ, Canada
[14] Hop Tenon, F-75970 Paris, France
[15] Hop Charles LeMoyne, Greenfield Pk, PQ, Canada
[16] Inst Mutualiste Montsouris, Dept Oncol, Paris, France
[17] GERCOR, Paris, France
[18] CHU Besancon, F-25030 Besancon, France
关键词
D O I
10.1200/jco.2013.31.4_suppl.448
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
448
引用
收藏
页数:1
相关论文
共 50 条
  • [1] Maintenance therapy with bevacizumab with or without erlotinib in metastatic colorectal cancer (mCRC) according to KRAS: Results of the GERCOR DREAM phase III trial.
    Tournigand, Christophe
    Chibaudel, Benoist
    Samson, Benoit
    Scheithauer, Werner
    Lledo, Gerard
    Viret, Frederic
    Andre, Thierry
    Ramee, Jean Francois
    Tubiana-Mathieu, Nicole
    Dauba, Jerome
    Dupuis, Olivier
    Rinaldi, Yves
    Mabro, May
    Aucoin, Nathalie
    Khalil, Ahmed
    Latreille, Jean
    Louvet, Christophe
    Brusquant, David
    Bonnetain, Franck
    de Gramont, Aimery
    JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (15)
  • [2] Bevacizumab (Bev) with or without erlotinib as maintenance therapy, following induction first-line chemotherapy plus Bev, in patients with metastatic colorectal cancer (mCRC): Efficacy and safety results of the international GERCOR DREAM phase III trial
    Tournigand, Christophe
    Samson, Benoit
    Scheithauer, Werner
    Lledo, Gerard
    Viret, Frederic
    Andre, Thierry
    Ramee, Jean Francois
    Tubiana-Mathieu, Nicole
    Dauba, Jerome
    Dupuis, Olivier
    Rinaldi, Yves
    Mabro, May
    Aucoin, Nathalie
    Khalil, Ahmed
    Latreille, Jean
    Louvet, Christophe
    Brusquant, David
    Bonnetain, Franck
    Chibaudel, Benoist
    De Gramont, Aimery
    JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (15)
  • [3] Erlotinib added to bevacizumab as maintenance therapy and health-related quality of life in patients with metastatic colorectal cancer: results of the GERCOR DREAM phase III trial
    Anota, Amelie
    Vernerey, Dewi
    Tournigand, Christophe
    Chibaudel, Benoist
    Samson, Benoit
    Scheithauer, Werner
    Brusquant, David
    Andre, Thierry
    de Gramont, Aimery
    Bonnetain, Franck
    QUALITY OF LIFE RESEARCH, 2016, 25 : 112 - 112
  • [4] A randomized phase III trial on maintenance treatment with bevacizumab (bev) alone or in combination with erlotinib (erlo) after chemotherapy and bev in metastatic colorectal cancer (mCRC)
    Johnsson, A.
    Frodin, J.
    Berglund, A.
    Hagman, H.
    Sundberg, J.
    Bergstrom, D.
    Christensen, R. D.
    Keldsen, N.
    Spindler, K. G.
    Jakobsen, A. K. M.
    JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (15)
  • [5] Erlotinib added to bevacizumab as maintenance therapy and health-related quality of life in patients with metastatic colorectal cancer: Results of the GERCOR DREAM phase III trial.
    Anota, Amelie
    Vernerey, Dewi
    Tournigand, Christophe
    Chibaudel, Benoist
    Samson, Benoit
    Scheithauer, Werner
    Brusquant, David
    Andre, Thierry
    De Gramont, Aimery
    Bonnetain, Franck
    JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (15)
  • [6] Bevacizumab with or without erlotinib as maintenance therapy in patients with metastatic colorectal cancer (GERCOR DREAM; OPTIMOX3): a randomised, open-label, phase 3 trial
    Tournigand, Christophe
    Chibaudel, Benoist
    Samson, Benoit
    Scheithauer, Werner
    Vernerey, Dewi
    Mesange, Paul
    Lledo, Gerard
    Viret, Frederic
    Ramee, Jean-Francois
    Tubiana-Mathieu, Nicole
    Dauba, Jerome
    Dupuis, Olivier
    Rinaldi, Yves
    Mabro, May
    Aucoin, Nathalie
    Latreille, Jean
    Bonnetain, Franck
    Louvet, Christophe
    Larsen, Annette K.
    Andre, Thierry
    de Gramont, Aimery
    LANCET ONCOLOGY, 2015, 16 (15): : 1493 - 1505
  • [7] Bevacizumab with or without erlotinib as maintenance therapy in patients with metastatic colorectal cancer (GERCOR DREAM; OPTIMOX3): a randomised, open-label, phase 3 trial (vol 16, pg 1493, 2015)
    Tournigand, C.
    Chibaudel, B.
    Samson, B.
    LANCET ONCOLOGY, 2015, 16 (16): : E589 - E589
  • [8] IMPACT OF KRAS STATUS ON SURVIVAL IN PATIENTS (PTS.) WITH METASTATIC COLORECTAL CANCER (MCRC) UNDERGOING BEVACIZUMAB (BEV) CONTAINING CHEMOTHERAPY REGIMEN-ANALYSIS OF THE AIO COLORECTAL CANCER STUDY GROUP
    Reinacher-Schick, A. C.
    Arnold, D.
    Kubicka, S.
    Hinke, A.
    Hegewisch-Becker, S.
    Geissler, M.
    Graeven, U.
    Schmoll, H.
    Schmiegel, W.
    Tannapfel, A.
    ANNALS OF ONCOLOGY, 2010, 21 : 190 - 190
  • [9] Phase II study of FOLFOX, bevacizumab and erlotinib as initial therapy for patients with metastatic colorectal cancer (MCRC).
    Meyerhardt, J. A.
    Stuart, K.
    Zhu, A.
    Fuchs, C.
    Bhargava, P.
    Earle, C.
    Blaszkowsky, L.
    Lawrence, C.
    Battu, S.
    Ryan, D. P.
    JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (18) : 157S - 157S
  • [10] A phase II trial of mFOLFOX-bevacizumab (bev) followed by single-agent axitinib (ax) as maintenance therapy for patients (pts) with first-line metastatic colorectal cancer (mCRC).
    Joseph, Mathew John
    Barnes, Kirk
    Blachly, Ronald
    Kuzur, Michel E.
    Bendell, Johanna C.
    JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (15)