Non-invasive markers associated with liver fibrosis in non-alcoholic fatty liver disease

被引：100
|
作者：
Guha, I. N.
Parkes, J.
Roderick, P. R.
Harris, S.
Rosenberg, W. M.
机构：
[1] Univ Southampton, Southampton Gen Hosp, Div Infect Inflammat & Repair, Liver Grp, Southampton SO16 6YD, Hants, England
[2] Univ Southampton, Southampton SO16 6YD, Hants, England
来源：
GUT | 2006年 / 55卷 / 11期
基金：
英国医学研究理事会;
关键词：
D O I：
10.1136/gut.2006.091454
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
The diagnosis of fibrosis within liver disease is important for prognosis, stratification for treatment, and monitoring of treatment efficacy. The rising incidence and prevalence of nonalcoholic fatty liver disease ( NAFLD) has driven the search for accurate non-invasive tools of liver fibrosis within this condition. With the aid of a systematic review, we explore how the field has evolved from the discovery of simple blood parameters to panel markers of liver fibrosis. We will discuss the biological plausibility, limitations, potential uses, and emerging diagnostic techniques of non-invasive markers in this rapidly expanding field.
引用
收藏
页码：1650 / 1660
页数：11
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