Suspended Manufacture of Biological Structures

被引：88
|
作者：
Moxon, Samuel R. [1 ]
Cooke, Megan E. [2 ,3 ]
Cox, Sophie C. [2 ]
Snow, Martyn [2 ,4 ]
Jeys, Lee [4 ]
Jones, Simon W. [3 ]
Smith, Alan M. [1 ]
Grover, Liam M. [2 ]
机构：
[1] Univ Huddersfield, Dept Pharm, Huddersfield HD1 3DH, W Yorkshire, England
[2] Univ Birmingham, Sch Chem Engn, Edgbaston B15 2TT, England
[3] Univ Birmingham, QE Hosp, MRC Musculoskeletal Ageing Ctr, Inst Inflammat & Ageing, Edgbaston B15 2WB, England
[4] Royal Orthopaed Hosp, Bristol Rd, Birmingham B31 2AP, W Midlands, England
来源：
ADVANCED MATERIALS | 2017年 / 29卷 / 13期
基金：
英国工程与自然科学研究理事会;
关键词：
ARTICULAR-CARTILAGE; HYDROGELS; KNEE; HYDROXYAPATITE; SCAFFOLD; DEFECTS; DESIGN; MODEL; BONE; GELS;
D O I：
10.1002/adma.201605594
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A method for the production of complex cell-laden structures is reported, which allows high-levels of spatial control over mechanical and chemical properties. The potential of this method for producing complicated tissues is demonstrated by manufacturing a complex hard/soft tissue interface and demonstrating that cell phenotype can be maintained over four weeks of culture.
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收藏
页数：6
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