Steroids for Acute Respiratory Distress Syndrome?

被引：36
|
作者：
Hough, Catherine L. [1 ]
机构：
[1] Univ Washington, Div Pulm & Crit Care Med, Harborview Med Ctr, Seattle, WA 98104 USA
来源：
CLINICS IN CHEST MEDICINE | 2014年 / 35卷 / 04期
关键词：
ARDS; Corticosteroids; Prevention; Treatment; Outcomes; INTENSIVE-CARE-UNIT; ACUTE LUNG INJURY; ACQUIRED-IMMUNODEFICIENCY-SYNDROME; PNEUMOCYSTIS-CARINII-PNEUMONIA; HIGH-DOSE METHYLPREDNISOLONE; POSTTRAUMATIC-STRESS; ADJUNCTIVE THERAPY; PULMONARY FIBROSIS; CRITICAL-APPRAISAL; CLINICAL-TRIAL;
D O I：
10.1016/j.ccm.2014.08.014
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
The development and severity of acute respiratory distress syndrome (ARDS) are closely related to dysregulated inflammation, and the duration of ARDS and eventual outcomes are related to persistent inflammation and abnormal fibroproliferation. Corticosteroids are potent modulators of inflammation and inhibitors of fibrosis that have been used since the first description of ARDS in attempts to improve outcomes. There is no evidence that corticosteroids prevent the development of ARDS among patients at risk. High-dose and short-course treatment with steroids does not improve the outcomes of patients with ARDS. Additional studies are needed to recommend treatment with steroids for ARDS.
引用
收藏
页码：781 / +
页数：16
相关论文
共 50 条
  • [1] Steroids in pediatric acute respiratory distress syndrome
    Monteverde-Fernandez, Nicolas
    Cristiani, Federico
    McArthur, Jenniffer
    Gonzalez-Dambrauskas, Sebastian
    ANNALS OF TRANSLATIONAL MEDICINE, 2019, 7 (19)
  • [2] Paralytics, Sedation, and Steroids in Acute Respiratory Distress Syndrome
    Leap, Jennifer
    Hill, Jared
    Patel, Kaushal
    Shah, Arpan
    Dumont, Tiffany
    CRITICAL CARE NURSING QUARTERLY, 2019, 42 (04) : 376 - 391
  • [3] Steroids and Immunomodulatory Therapies for Acute Respiratory Distress Syndrome
    Millar, Jonathan E.
    Craven, Thomas H.
    Shankar-Hari, Manu
    CLINICS IN CHEST MEDICINE, 2024, 45 (04) : 885 - 894
  • [4] Steroids to Soften the Blow in Persistent Acute Respiratory Distress Syndrome
    Shaz, David
    Pastores, Stephen M.
    CRITICAL CARE MEDICINE, 2018, 46 (06) : 1011 - 1012
  • [5] Steroids and β-Agonists in Acute Respiratory Distress Syndrome: Timing Is Everything
    Englert, Joshua A.
    Crouser, Elliott D.
    CRITICAL CARE MEDICINE, 2017, 45 (05) : 914 - 915
  • [6] Acute respiratory distress syndrome. Role of steroids.
    Irrazabal, CL
    Capidevila, AA
    Sosa, C
    Khoury, MC
    Jorge, MA
    Gherardi, CR
    MEDICINA-BUENOS AIRES, 2004, 64 (03) : 250 - 256
  • [7] Steroids in fibroproliferative acute respiratory distress syndrome: approach with care
    Ewanchuk, Mark A.
    Jacka, Michael T.
    CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 2007, 54 (09): : 765 - 766
  • [8] Steroids in fibroproliferative acute respiratory distress syndrome: approach with care
    Mark A. Ewanchuk
    Michael J. Jacka
    Canadian Journal of Anesthesia, 2007, 54 : 765 - 766
  • [9] Acute respiratory distress syndrome and steroids in the shadow of coronavirus disease 2019
    Jaeschke, Roman
    POLISH ARCHIVES OF INTERNAL MEDICINE-POLSKIE ARCHIWUM MEDYCYNY WEWNETRZNEJ, 2020, 130 (04): : 266 - 267
  • [10] Investigation of the Cardiotonic Steroids, Marinobufagenin and Resibufogenin, in the Acute Respiratory Distress Syndrome
    Abbas, Mir Mohammad Kamran
    Chen, Qingzheng
    Das, Aayudh
    Oliver, Joel
    Jiang, Weiwu
    Moorthy, Bhagavatula
    Patel, Bela
    Morin, Kristi
    Puschett, Jules
    FASEB JOURNAL, 2016, 30
12345