Montelukast in allergic rhinitis: a systematic review and meta-analysis

被引：50
|
作者：
Grainger, J. [1 ]
Drake-Lee, A. [1 ]
机构：
[1] Univ Hosp Birmingham, Queen Elizabeth Hosp, Dept Otorhinolaryngol, Birmingham, W Midlands, England
来源：
CLINICAL OTOLARYNGOLOGY | 2006年 / 31卷 / 05期
关键词：
D O I：
10.1111/j.1749-4486.2006.01276.x
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
Allergic rhinitis is common. This systematic review outlines the evidence regarding montelukast in allergic rhinitis and provides a meta-analysis of its efficacy. The evidence suggests that montelukast does reduce nasal symptom score by 3.4% (95% CI: 2.5% to 4.2%) when compared with placebo. Montelukast is not as effective as topical nasal steroids or antihistamines and should therefore be regarded as second line therapy. When used, montelukast should be used in combination with an antihistamine.
引用
收藏
页码：360 / 367
页数：8
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