Platelet Activity and Outcome after Intracerebral Hemorrhage

被引：61

作者：

Naidech, Andrew M. ^{[1
]}

Bernstein, Richard A. ^{[1
]}

Levasseur, Kimberly ^{[3
]}

Bassin, Sarice L. ^{[1
]}

Bendok, Bernard R. ^{[2
]}

Batjer, H. Hunt ^{[2
]}

Bleck, Thomas P. ^{[3
]}

Alberts, Mark J. ^{[1
]}

机构：

[1] Northwestern Univ, Dept Neurol, Chicago, IL 60611 USA

[2] Northwestern Univ, Dept Neurol Surg, Chicago, IL 60611 USA

[3] Evanston NW Healthcare, NW Mem Hosp, Chicago, IL USA

来源：

ANNALS OF NEUROLOGY | 2009年 / 65卷 / 03期

关键词：

NONSTEROIDAL ANTIINFLAMMATORY DRUGS; INDEPENDENT PREDICTOR; ANTIPLATELET THERAPY; ASPIRIN; RISK; CLOPIDOGREL; STROKE; ONSET;

D O I：

10.1002/ana.21618

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

There are few data on platelet function in intracerebral hemorrhage (ICH). We prospectively enrolled 69 patients with ICH and measured platelet function on admission. Aspirin use before ICH was associated with reduced platelet activity. Less platelet activity was associated with intraventricular hemorrhage (516.5 [interquartile range (IQR), 454-629.25] vs 637 [IQR, 493-654] aspirin reaction units; p = 0.04) and death at 14 days (480.5 [IQR, 444.5-632.5] vs 626 [IQR, 494-652] aspirin reaction units; p = 0.04). Objective measures of platelet function on admission are associated with intraventricular hemorrhage and death after ICH.

引用

页码：352 / 356

页数：5

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