Potential Microfluidic Devices for COVID-19 Antibody Detection at Point-of-Care (POC): A Review

被引：28
|
作者：
Tayyab, Muhammad [1 ]
Sami, Muhammad Ahsan [1 ]
Raji, Hassan [1 ]
Mushnoori, Srinivas [2 ]
Javanmard, Mehdi [1 ]
机构：
[1] Rutgers State Univ, Dept Elect & Comp Engn, Piscataway, NJ 08854 USA
[2] Rutgers State Univ, Dept Chem & Biochem Engn, Piscataway, NJ 08854 USA
来源：
IEEE SENSORS JOURNAL | 2021年 / 21卷 / 04期
基金：
美国国家科学基金会;
关键词：
COVID-19; Immune system; Viruses (medical); Testing; Proteins; Sensors; Microfluidics; Antibody; biosensors; chemical and biological sensors; enzyme linked immunosorbent assay (ELISA); protein;
D O I：
10.1109/JSEN.2020.3034892
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
COVID-19 has been declared a global pandemic which has brought the world economy and the society to a standstill. The current emphasis of testing is on detection of genetic material of SARS-CoV-2. Such tests are useful for assessing the current state of a subject: Infected or not infected. In addition to such tests, antibody testing is necessary to stratify the population into three groups: never exposed, infected, and immune. Such a stratification is necessary for safely reopening the society and remobilizing the economy. The aim of this review article is to inform the audience of the current diagnostic and surveillance technologies that are being employed for the detection of SARS-CoV-2 antibodies along with their shortcomings, and to highlight microfluidic sensors and devices that show promise of being commercialized for detection and quantification of SARS-CoV-2 antibodies in low-resource and Point-of-Care (POC) settings.
引用
收藏
页码：4007 / 4017
页数：11
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