FECAL MICROBIOTA TRANSPLANTATION IN CHILDREN WITH RECURENT CLOSTRIDIUM DIFFICILE INFECTION

被引：28
|
作者：
Pierog, Anne [1 ]
Mencin, Ali [1 ]
Reilly, Norelle Rizkalla [1 ]
机构：
[1] Columbia Univ, Med Ctr, Div Pediat Gastroentrol Hepatol & Nutr, New York, NY USA
来源：
PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2014年 / 33卷 / 11期
关键词：
microbiome; stool infection; colonoscopy; CASE SERIES; DIARRHEA;
D O I：
10.1097/INF.0000000000000419
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Clostridium difficile eradication using fecal microbiota transplantation (FMT) has been successful in adults but little information is available in pediatrics. We report 6 pediatric patients with refractory C. difficile cured by FMT with no recurrences to date. Our results demonstrate that FMT can be an effective treatment for refractory C. difficile infection in pediatrics. Long-term safety and efficacy need to be studied.
引用
收藏
页码：1198 / 1200
页数：4
相关论文
共 50 条
  • [1] Efficacy of Fecal Microbiota Transplantation for Clostridium difficile Infection in Children
    Nicholson, Maribeth R.
    Mitchell, Paul D.
    Alexander, Erin
    Ballal, Sonia
    Bartlett, Mark
    Becker, Penny
    Davidovics, Zev
    Docktor, Michael
    Dole, Michael
    Felix, Grace
    Gisser, Jonathan
    Hourigan, Suchitra K.
    Jensen, M. Kyle
    Kaplan, Jess L.
    Kelsen, Judith
    Kennedy, Melissa
    Khanna, Sahil
    Knackstedt, Elizabeth
    Leier, McKenzie
    Lewis, Jeffery
    Lodarek, Ashley
    Michail, Sonia
    Oliva-Hemker, Maria
    Patton, Tiffany
    Queliza, Karen
    Russell, George H.
    Singh, Namita
    Solomon, Aliza
    Suskind, David L.
    Werlin, Steven
    Kellermayer, Richard
    Kahn, Stacy A.
    [J]. CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2020, 18 (03) : 612 - +
  • [2] Fecal microbiota transplantation for recurrent Clostridium difficile infection in children
    Chen, Becky
    Avinashi, Vishal
    Dobson, Simon
    [J]. JOURNAL OF INFECTION, 2017, 74 : S120 - S127
  • [3] Fecal Microbiota Transplantation for Clostridium difficile Infection
    Armstrong, Matthew J.
    Pathmakanthan, Shrikanth
    Iqbal, Tariq H.
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2015, 313 (07): : 725 - 726
  • [4] Fecal Fixation: Fecal Microbiota Transplantation for Clostridium difficile Infection
    Johnson, Stuart
    Gerding, Dale N.
    [J]. CLINICAL INFECTIOUS DISEASES, 2017, 64 (03) : 272 - 274
  • [5] Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection
    Brandt, Lawrence J.
    Reddy, Sheela S.
    [J]. JOURNAL OF CLINICAL GASTROENTEROLOGY, 2011, 45 : S159 - S167
  • [6] Fecal microbiota transplantation for management of Clostridium difficile infection
    Vaishnavi C.
    [J]. Indian Journal of Gastroenterology, 2014, 33 (4) : 301 - 307
  • [7] Fecal Microbiota Transplantation for the Management of Clostridium difficile Infection
    Rao, Krishna
    Young, Vincent B.
    [J]. INFECTIOUS DISEASE CLINICS OF NORTH AMERICA, 2015, 29 (01) : 109 - +
  • [8] Fecal Microbiota Transplantation for Clostridium difficile Infection Reply
    Youngster, Ilan
    Hohmann, Elizabeth L.
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2015, 313 (07): : 726 - 726
  • [9] Fecal Microbiota Transplantation for the Management of Clostridium difficile Infection
    Paknikar, Raghavendra
    Pekow, Joel
    [J]. SURGICAL INFECTIONS, 2018, 19 (08) : 785 - 791
  • [10] Fecal Microbiota Transplantation for Primary Clostridium difficile Infection
    Juul, Frederik E.
    Garborg, Kjetil
    Bretthauer, Michael
    Skudal, Hilde
    Oines, Mari N.
    Wiig, Havard
    Rose, Oystein
    Seip, Birgitte
    Lamont, J. Thomas
    Midtvedt, Tore
    Valeur, Jorgen
    Kalager, Mette
    Holme, Oyvind
    Helsingen, Lise
    Loberg, Magnus
    Adami, Hans-Olov
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2018, 378 (26): : 2535 - +
12345