Pharmaceutical Equivalence of Metronidazole 500 mg Tablets

被引：0
|
作者：
Volonte, Maria G. [1 ]
Ruiz, Esperanza [1 ]
Rubini, Agustina [1 ]
Pozzo, Ricardo [1 ]
机构：
[1] Natl Univ La Plata, Fac Ciencias Exactas, Catedra Control Calidad Medicamentos, RA-1900 La Plata, Buenos Aires, Argentina
来源：
LATIN AMERICAN JOURNAL OF PHARMACY | 2008年 / 27卷 / 06期
关键词：
Antibiotic; Metronidazole; Pharmaceutical equivalents;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Metronidazole (MTZ) is widely used as antiprotozoal, antiamebic and antibacterial drug to treat a broad range of infections caused by anaerobic protists and bacteria. The aim of this study was to compare the fourteen products, MTZ tablets 500 mg, which were available in the argentine pharmaceutical market, looking to the pharmaceutical equivalence between them. The following tests were made: evaluation of packaging specifications, description of tablets, identification and quantification, uniformity of dosage units, dissolution test and dissolution profiles. We conclude that there is not pharmaceutical equivalence between all the studied products at the moment of the present study.
引用
收藏
页码：887 / 893
页数：7
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