CHRONIC HEPATITIS-C;
INTERFERON-ALPHA-2B PLUS RIBAVIRIN;
VIRUS-INFECTED PATIENTS;
ACTIVE ANTIRETROVIRAL THERAPY;
LIVER-RELATED MORTALITY;
HEPATOCELLULAR-CARCINOMA;
NATURAL-HISTORY;
IMMUNODEFICIENCY;
PROGRESSION;
TRIAL;
D O I:
10.1016/S0399-8320(09)72446-7
中图分类号:
R57 [消化系及腹部疾病];
学科分类号:
摘要:
Hepatitis C virus (HCV) infection remains a major concern in human immunodeficiency virus (HIV) infected people because of its prevalence and clinical consequences. Management of these patients has evolved, becoming more and more demanding on therapeutic goals and means, not only regarding antiretroviral therapy but also anti-HCV therapy. Thus, if the results of current management are encouraging, they nevertheless is insufficient. It underlines the imperative need for a better comprehension of the essential elements of HCV-HIV co-infection natural history and of the determinants of response to HCV therapy, in particular with pivotal, studies such as the ANRS HC 02 RIBAVIC trial. (C) 2009 Elsevier Masson SAS. All rights reserved.
机构:
Univ Buenos Aires, Hosp Clin Jose De San Martin, RA-1053 Buenos Aires, DF, ArgentinaUniv Buenos Aires, Hosp Clin Jose De San Martin, RA-1053 Buenos Aires, DF, Argentina