Metabolic syndrome and rheumatic diseases

Aim. To characterize prevalence and features of rheumatic diseases in patients with metabolic syndrome, metabolic disturbances in patients with rheumatic diseases (RD), to ascertain their most frequent variants and characteristics. Material and methods. After examination of 1291 therapeutic patients 19 to 79 years of age for metabolic syndrome (MS), those with MS were screened for RD. In parallel, 1212 RD patients were studied for associated pathology: arterial hypertension, coronary heart disease, obesity, dyslipidemia, hyperuricemia and other components of MS. A separate electronic matrix was created for each of the two groups. Statistics were obtained using standard programs Statistica 6.0 and MS Excel 2000 for Windows XP 2000. Results. MS was detected in 317 (24.6%) patients seeking medical advice (mean age 54.11 +/- 0.59 years). MS was complete in 272 (85.8%) patients, 287 (90.5%) had arthralgia, 131 (41.3%) - episodes of painful joints swelling in the presence of family history. RD were detected in 295 (93.1%) MS patients. Osteoarthrosis, osteochondrosis and systemic osteoporosis occurred most often. Various metabolic disorders occurred in all the examinees with RD. The disorders were most pronounced in patients with gout and osteoarthrosis. Conclusion. MS patients comprise a group of a high risk for RD, especially gout and osteoarthrosis.