Compressive Sensing Based Hyperspectral Bioluminescent Imaging

Photonics based imaging is a widely utilised technique for the study of biological functions within pre-clinical studies. It is a sensitive and non-invasive technique that is able to detect distributed (biologically informative) visible and near-infrared light sources providing information about biological function. Compressive Sensing (CS) is a method of signal processing that works on the basis that a signal or image can be compressed without important information being lost. This work describes the development of a CS based hyperspectral Bioluminescence imaging system that can be used to collect compressed fluence data from the external surface of an animal model, due to an internal source, providing lower acquisition times, higher spectral content and potentially better tomographic source localisation.