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- [1] PI3K/p110δ is a novel therapeutic target in multiple myeloma[J]. BLOOD, 2010, 116 (09) : 1460 - 1468Ikeda, Hiroshi论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USA Harvard Univ, Sch Med, Lebow Inst Myeloma Therapeut, Boston, MA 02115 USA Sapporo Med Univ, Dept Internal Med 1, Sapporo, Hokkaido, Japan Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USAHideshima, Teru论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USA Harvard Univ, Sch Med, Lebow Inst Myeloma Therapeut, Boston, MA 02115 USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USAFulciniti, Mariateresa论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USA Harvard Univ, Sch Med, Lebow Inst Myeloma Therapeut, Boston, MA 02115 USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USAPerrone, Giulia论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USA Harvard Univ, Sch Med, Lebow Inst Myeloma Therapeut, Boston, MA 02115 USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USAMiura, Naoya论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USA Harvard Univ, Sch Med, Lebow Inst Myeloma Therapeut, Boston, MA 02115 USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USAYasui, Hiroshi论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USA Harvard Univ, Sch Med, Lebow Inst Myeloma Therapeut, Boston, MA 02115 USA Sapporo Med Univ, Dept Internal Med 1, Sapporo, Hokkaido, Japan Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USAOkawa, Yutaka论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USA Harvard Univ, Sch Med, Lebow Inst Myeloma Therapeut, Boston, MA 02115 USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USAKiziltepe, Tanyel论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USA Harvard Univ, Sch Med, Lebow Inst Myeloma Therapeut, Boston, MA 02115 USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USASanto, Loredana论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USA Harvard Univ, Sch Med, Lebow Inst Myeloma Therapeut, Boston, MA 02115 USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USAVallet, Sonia论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USA Harvard Univ, Sch Med, Lebow Inst Myeloma Therapeut, Boston, MA 02115 USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USACristea, Diana论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USA Harvard Univ, Sch Med, Lebow Inst Myeloma Therapeut, Boston, MA 02115 USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USACalabrese, Elisabetta论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USA Harvard Univ, Sch Med, Lebow Inst Myeloma Therapeut, Boston, MA 02115 USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USAGorgun, Gullu论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USA Harvard Univ, Sch Med, Lebow Inst Myeloma Therapeut, Boston, MA 02115 USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USARaje, Noopur S.论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USA Harvard Univ, Sch Med, Lebow Inst Myeloma Therapeut, Boston, MA 02115 USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USARichardson, Paul论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USA Harvard Univ, Sch Med, Lebow Inst Myeloma Therapeut, Boston, MA 02115 USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USAMunshi, Nikhil C.论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USA Harvard Univ, Sch Med, Lebow Inst Myeloma Therapeut, Boston, MA 02115 USA Boston VA Healthcare Syst, W Roxbury, MA USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USALannutti, Brian J.论文数: 0 引用数: 0 h-index: 0机构: Calistoga Pharmaceut Inc, Seattle, WA USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USAPuri, Kamal D.论文数: 0 引用数: 0 h-index: 0机构: Calistoga Pharmaceut Inc, Seattle, WA USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USAGiese, Neill A.论文数: 0 引用数: 0 h-index: 0机构: Calistoga Pharmaceut Inc, Seattle, WA USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USAAnderson, Kenneth C.论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USA Harvard Univ, Sch Med, Lebow Inst Myeloma Therapeut, Boston, MA 02115 USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USA
- [2] Angiogenesis selectively requires the p110α isoform of PI3K to control endothelial cell migration[J]. NATURE, 2008, 453 (7195) : 662 - 666Graupera, Mariona论文数: 0 引用数: 0 h-index: 0机构: Queen Mary Univ London, Ctr Cell Signalling, Inst Canc, London EC1M 6BQ, England Canc Res UK London Res Inst, Vasc Biol Lab, London WC2A 3PX, EnglandGuillermet-Guibert, Julie论文数: 0 引用数: 0 h-index: 0机构: Queen Mary Univ London, Ctr Cell Signalling, Inst Canc, London EC1M 6BQ, England Canc Res UK London Res Inst, Vasc Biol Lab, London WC2A 3PX, EnglandFoukas, Lazaros C.论文数: 0 引用数: 0 h-index: 0机构: Queen Mary Univ London, Ctr Cell Signalling, Inst Canc, London EC1M 6BQ, England Canc Res UK London Res Inst, Vasc Biol Lab, London WC2A 3PX, EnglandPhng, Li-Kun论文数: 0 引用数: 0 h-index: 0机构: Canc Res UK London Res Inst, Vasc Biol Lab, London WC2A 3PX, England Canc Res UK London Res Inst, Vasc Biol Lab, London WC2A 3PX, EnglandCain, Robert J.论文数: 0 引用数: 0 h-index: 0机构: Kings Coll London, Randall Div Cell & Mol Biophys, London SE1 1UL, England Canc Res UK London Res Inst, Vasc Biol Lab, London WC2A 3PX, EnglandSalpekar, Ashreena论文数: 0 引用数: 0 h-index: 0机构: Queen Mary Univ London, Ctr Cell Signalling, Inst Canc, London EC1M 6BQ, England Canc Res UK London Res Inst, Vasc Biol Lab, London WC2A 3PX, EnglandPearce, Wayne论文数: 0 引用数: 0 h-index: 0机构: Queen Mary Univ London, Ctr Cell Signalling, Inst Canc, London EC1M 6BQ, England Canc Res UK London Res Inst, Vasc Biol Lab, London WC2A 3PX, EnglandMeek, Stephen论文数: 0 引用数: 0 h-index: 0机构: Univ Edinburgh, Gene Targeting Lab, Inst Stem Cell Res, Edinburgh EH9 3JQ, Midlothian, Scotland Canc Res UK London Res Inst, Vasc Biol Lab, London WC2A 3PX, EnglandMillan, Jaime论文数: 0 引用数: 0 h-index: 0机构: Kings Coll London, Randall Div Cell & Mol Biophys, London SE1 1UL, England Canc Res UK London Res Inst, Vasc Biol Lab, London WC2A 3PX, EnglandCutillas, Pedro R.论文数: 0 引用数: 0 h-index: 0机构: Queen Mary Univ London, Ctr Cell Signalling, Inst Canc, London EC1M 6BQ, England Canc Res UK London Res Inst, Vasc Biol Lab, London WC2A 3PX, EnglandSmith, Andrew J. H.论文数: 0 引用数: 0 h-index: 0机构: Univ Edinburgh, Gene Targeting Lab, Inst Stem Cell Res, Edinburgh EH9 3JQ, Midlothian, Scotland Canc Res UK London Res Inst, Vasc Biol Lab, London WC2A 3PX, EnglandRidley, Anne J.论文数: 0 引用数: 0 h-index: 0机构: Kings Coll London, Randall Div Cell & Mol Biophys, London SE1 1UL, England Canc Res UK London Res Inst, Vasc Biol Lab, London WC2A 3PX, EnglandRuhrberg, Christiana论文数: 0 引用数: 0 h-index: 0机构: UCL, Dept Cell Biol, Inst Ophthalmol, London EC1V 9EL, England Canc Res UK London Res Inst, Vasc Biol Lab, London WC2A 3PX, EnglandGerhardt, Holger论文数: 0 引用数: 0 h-index: 0机构: Canc Res UK London Res Inst, Vasc Biol Lab, London WC2A 3PX, England Canc Res UK London Res Inst, Vasc Biol Lab, London WC2A 3PX, EnglandVanhaesebroeck, Bart论文数: 0 引用数: 0 h-index: 0机构: Queen Mary Univ London, Ctr Cell Signalling, Inst Canc, London EC1M 6BQ, England Canc Res UK London Res Inst, Vasc Biol Lab, London WC2A 3PX, England
- [3] Angiogenesis selectively requires the p110α isoform of PI3K to control endothelial cell migration[J]. Nature, 2008, 453 : 662 - 666Mariona Graupera论文数: 0 引用数: 0 h-index: 0机构: Centre for Cell Signalling,Randall Division of Cell and Molecular BiophysicsJulie Guillermet-Guibert论文数: 0 引用数: 0 h-index: 0机构: Centre for Cell Signalling,Randall Division of Cell and Molecular BiophysicsLazaros C. Foukas论文数: 0 引用数: 0 h-index: 0机构: Centre for Cell Signalling,Randall Division of Cell and Molecular BiophysicsLi-Kun Phng论文数: 0 引用数: 0 h-index: 0机构: Centre for Cell Signalling,Randall Division of Cell and Molecular BiophysicsRobert J. Cain论文数: 0 引用数: 0 h-index: 0机构: Centre for Cell Signalling,Randall Division of Cell and Molecular BiophysicsAshreena Salpekar论文数: 0 引用数: 0 h-index: 0机构: Centre for Cell Signalling,Randall Division of Cell and Molecular BiophysicsWayne Pearce论文数: 0 引用数: 0 h-index: 0机构: Centre for Cell Signalling,Randall Division of Cell and Molecular BiophysicsStephen Meek论文数: 0 引用数: 0 h-index: 0机构: Centre for Cell Signalling,Randall Division of Cell and Molecular BiophysicsJaime Millan论文数: 0 引用数: 0 h-index: 0机构: Centre for Cell Signalling,Randall Division of Cell and Molecular BiophysicsPedro R. Cutillas论文数: 0 引用数: 0 h-index: 0机构: Centre for Cell Signalling,Randall Division of Cell and Molecular BiophysicsAndrew J. H. Smith论文数: 0 引用数: 0 h-index: 0机构: Centre for Cell Signalling,Randall Division of Cell and Molecular BiophysicsAnne J. Ridley论文数: 0 引用数: 0 h-index: 0机构: Centre for Cell Signalling,Randall Division of Cell and Molecular BiophysicsChristiana Ruhrberg论文数: 0 引用数: 0 h-index: 0机构: Centre for Cell Signalling,Randall Division of Cell and Molecular BiophysicsHolger Gerhardt论文数: 0 引用数: 0 h-index: 0机构: Centre for Cell Signalling,Randall Division of Cell and Molecular BiophysicsBart Vanhaesebroeck论文数: 0 引用数: 0 h-index: 0机构: Centre for Cell Signalling,Randall Division of Cell and Molecular Biophysics
- [4] CAL-101: A Selective Inhibitor of PI3K p110δ for the Treatment of Multiple Myeloma[J]. CLINICAL LYMPHOMA & MYELOMA, 2009, 9 : S98 - S99Ikeda, H.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USA Dana Farber Canc Inst, Boston, MA USAHideshima, T.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USA Dana Farber Canc Inst, Boston, MA USAFulciniti, M.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USA Dana Farber Canc Inst, Boston, MA USAPerrone, G.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USA Dana Farber Canc Inst, Boston, MA USAOkawa, Y.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USA Dana Farber Canc Inst, Boston, MA USAYasui, H.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USA Dana Farber Canc Inst, Boston, MA USAVallet, S.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USA Dana Farber Canc Inst, Boston, MA USASanto, L.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USA Dana Farber Canc Inst, Boston, MA USACristina, D.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USA Dana Farber Canc Inst, Boston, MA USAGorgun, G.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USA Dana Farber Canc Inst, Boston, MA USACalabrese, E.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USA Dana Farber Canc Inst, Boston, MA USARaje, N. S.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USA Dana Farber Canc Inst, Boston, MA USARichardson, P. G.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USA Dana Farber Canc Inst, Boston, MA USAMunshi, N. C.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USA Dana Farber Canc Inst, Boston, MA USALannutti, B.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USAPuri, K.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USAGiese, N.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USAAnderson, K. C.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USA Dana Farber Canc Inst, Boston, MA USA
- [5] Involvement of the p110α Isoform of PI3K in Early Development of Mouse Embryos[J]. MOLECULAR REPRODUCTION AND DEVELOPMENT, 2009, 76 (04) : 389 - 398Xu, Xiao-Yan论文数: 0 引用数: 0 h-index: 0机构: China Med Univ, Dept Biochem & Mol Biol, Shenyang 110001, Liaoning, Peoples R China China Med Univ, Dept Biochem & Mol Biol, Shenyang 110001, Liaoning, Peoples R ChinaZhang, Zhe论文数: 0 引用数: 0 h-index: 0机构: China Med Univ, Dept Biochem & Mol Biol, Shenyang 110001, Liaoning, Peoples R China China Med Univ, Dept Biochem & Mol Biol, Shenyang 110001, Liaoning, Peoples R ChinaSu, Wen-Hui论文数: 0 引用数: 0 h-index: 0机构: China Med Univ, Dept Biochem & Mol Biol, Shenyang 110001, Liaoning, Peoples R China China Med Univ, Dept Biochem & Mol Biol, Shenyang 110001, Liaoning, Peoples R China论文数: 引用数: h-index:机构:论文数: 引用数: h-index:机构:Zhao, Hong-Mei论文数: 0 引用数: 0 h-index: 0机构: China Med Univ, Dept Biochem & Mol Biol, Shenyang 110001, Liaoning, Peoples R China China Med Univ, Dept Biochem & Mol Biol, Shenyang 110001, Liaoning, Peoples R ChinaZong, Zhi-Hong论文数: 0 引用数: 0 h-index: 0机构: China Med Univ, Dept Biochem & Mol Biol, Shenyang 110001, Liaoning, Peoples R China China Med Univ, Dept Biochem & Mol Biol, Shenyang 110001, Liaoning, Peoples R China论文数: 引用数: h-index:机构:Yu, Bing-Zhi论文数: 0 引用数: 0 h-index: 0机构: China Med Univ, Dept Biochem & Mol Biol, Shenyang 110001, Liaoning, Peoples R China China Med Univ, Dept Biochem & Mol Biol, Shenyang 110001, Liaoning, Peoples R China
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- [7] p37δ is a new isoform of PI3K p110δ that increases cell proliferation and is overexpressed in tumors[J]. ONCOGENE, 2012, 31 (27) : 3277 - 3286Fransson, S.论文数: 0 引用数: 0 h-index: 0机构: Univ Gothenburg, Sahlgrenska Canc Ctr, Dept Med & Clin Genet, SE-40530 Gothenburg, Sweden Univ Gothenburg, Sahlgrenska Canc Ctr, Dept Med & Clin Genet, SE-40530 Gothenburg, SwedenUv, A.论文数: 0 引用数: 0 h-index: 0机构: Univ Gothenburg, Sahlgrenska Canc Ctr, Dept Med & Clin Genet, SE-40530 Gothenburg, Sweden Univ Gothenburg, Sahlgrenska Canc Ctr, Dept Med & Clin Genet, SE-40530 Gothenburg, SwedenEriksson, H.论文数: 0 引用数: 0 h-index: 0机构: Univ Gothenburg, Sahlgrenska Canc Ctr, Dept Med & Clin Genet, SE-40530 Gothenburg, Sweden Univ Gothenburg, Sahlgrenska Canc Ctr, Dept Med & Clin Genet, SE-40530 Gothenburg, SwedenAndersson, M. K.论文数: 0 引用数: 0 h-index: 0机构: Univ Gothenburg, Sahlgrenska Canc Ctr, Dept Pathol, SE-40530 Gothenburg, Sweden Univ Gothenburg, Sahlgrenska Canc Ctr, Dept Med & Clin Genet, SE-40530 Gothenburg, SwedenWettergren, Y.论文数: 0 引用数: 0 h-index: 0机构: Univ Gothenburg, Dept Gen Surg, SE-40530 Gothenburg, Sweden Univ Gothenburg, Sahlgrenska Canc Ctr, Dept Med & Clin Genet, SE-40530 Gothenburg, SwedenBergo, M.论文数: 0 引用数: 0 h-index: 0机构: Univ Gothenburg, Sahlgrenska Canc Ctr, Dept Med, SE-40530 Gothenburg, Sweden Univ Gothenburg, Sahlgrenska Canc Ctr, Dept Med & Clin Genet, SE-40530 Gothenburg, SwedenEjeskar, K.论文数: 0 引用数: 0 h-index: 0机构: Univ Gothenburg, Sahlgrenska Canc Ctr, Dept Med & Clin Genet, SE-40530 Gothenburg, Sweden Univ Skovde, Sch Life Sci, Skovde, Sweden Univ Gothenburg, Sahlgrenska Canc Ctr, Dept Med & Clin Genet, SE-40530 Gothenburg, Sweden
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