Near-infrared spectroscopy as a tool to improve quality

被引:21
|
作者
Plugge, W [1 ]
vanderVlies, C [1 ]
机构
[1] GIST BROCADES BV,IND PHARMACEUT PROD DIV,NL-2600 MA DELFT,NETHERLANDS
关键词
lactose NIR spectroscopy; pharmaceutical substances; polar qualification system; quality point; validation;
D O I
10.1016/S0731-7085(96)01782-7
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Near-infrared spectroscopy, together with a polar qualification system, is an ideal technique to distinguish between identical pharmaceutical substances differing only slightly in chemical or physical characteristics. Among the attractive applications of this powerful combination are the more precise definition and selection of starting materials used in the manufacturing of medicinal products and its use in blending validation.
引用
收藏
页码:891 / 898
页数:8
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