Plasma serotonin in horses undergoing surgery for small intestinal colic

被引：0
|
作者：
Torfs, Sara C. [1 ]
Maes, An A. [2 ]
Delesalle, Catherine J. [1 ,3 ]
Pardon, Bart [1 ]
Croubels, Siska M. [2 ]
Deprez, Piet [1 ]
机构：
[1] Univ Ghent, Dept Large Anim Internal Med & Clin Biol, Fac Vet Med, B-9820 Merelbeke, Belgium
[2] Univ Ghent, Dept Pharmacol Toxicol & Biochem, Fac Vet Med, B-9820 Merelbeke, Belgium
[3] Univ Utrecht, Dept Equine Sci, Fac Vet Med, NL-3584 CL Utrecht, Netherlands
来源：
CANADIAN VETERINARY JOURNAL-REVUE VETERINAIRE CANADIENNE | 2015年 / 56卷 / 02期
关键词：
IRRITABLE-BOWEL-SYNDROME; BETA-THROMBOGLOBULIN; POSTOPERATIVE ILEUS; SEASONAL-CHANGES; RISK-FACTORS; IN-VITRO; INJURY; REPERFUSION; CORTISOL; 5-HT;
D O I：
暂无
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
This study compared serotonin concentrations in platelet poor plasma (PPP) from healthy horses and horses with surgical small intestinal (SI) colic, and evaluated their association with postoperative ileus, strangulation and non-survival. Plasma samples (with EDTA) from 33 horses with surgical SI colic were collected at several pre- and post-operative time points. Serotonin concentrations were determined using liquid-chromatography tandem mass spectrometry. Results were compared with those for 24 healthy control animals. The serotonin concentrations in PPP were sighificantly lower (P < 0.01) in pre- and post-operative samples from surgical SI colic horses compared to controls. However, no association with postoperative ileus or non-survival could be demonstrated at any time point. In this clinical study, plasma serotonin was not a suitable prognostic factor in horses with SI surgical colic.
引用
收藏
页码：178 / 184
页数：7
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