A multicentre, international, randomised, open-label phase 3 trial of avelumab plus best supportive care (BSC) vs BSC alone as maintenance therapy after first-line platinum-based chemotherapy in patients with advanced urothelial cancer (JAVELIN bladder 100)

被引:5
|
作者
Powles, T. [1 ]
Grivas, P. [2 ]
Aragon-Ching, J. B. [3 ]
Faroun, Y. [4 ]
Kessler, E. R. [5 ]
Tomita, Y. [6 ]
Chakrabarti, D. [7 ]
Laliberte, R. J. [7 ]
Shnaidman, M. [7 ]
Petrylak, D. [8 ]
机构
[1] Royal Free Hosp, Med Oncol, London, England
[2] Cleveland Clin, Med Oncol, Cleveland, OH 44106 USA
[3] Inova Schar Canc Inst, Med Oncol, Fairfax, VA USA
[4] St Lukes Hosp & Hlth Network, Med Oncol, Bethlehem, PA USA
[5] Univ Colorado, Med Oncol, Anschutz Med Campus, Aurora, CO USA
[6] Niigata Univ, Grad Sch Med & Dent Sci, Urol, Niigata, Japan
[7] Pfizer Inc, Res, New York, NY USA
[8] Yale Canc Ctr, Med Oncol, New Haven, CT USA
关键词
D O I
10.1093/annonc/mdw373.69
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
842TiP
引用
收藏
页数:1
相关论文
共 50 条
  • [1] Avelumab first-line maintenance plus best supportive care (BSC) vs BSC alone for advanced urothelial carcinoma: JAVELIN Bladder 100 Japanese subgroup analysis
    Yoshihiko Tomita
    Yoshiaki Yamamoto
    Norihiko Tsuchiya
    Hiroomi Kanayama
    Masatoshi Eto
    Hideaki Miyake
    Thomas Powles
    Mizuki Yoshida
    Yuichiro Koide
    Yoshiko Umeyama
    Alessandra di Pietro
    Hirotsugu Uemura
    [J]. International Journal of Clinical Oncology, 2022, 27 : 383 - 395
  • [2] Avelumab first-line maintenance plus best supportive care (BSC) vs BSC alone for advanced urothelial carcinoma: JAVELIN Bladder 100 Japanese subgroup analysis
    Tomita, Yoshihiko
    Yamamoto, Yoshiaki
    Tsuchiya, Norihiko
    Kanayama, Hiroomi
    Eto, Masatoshi
    Miyake, Hideaki
    Powles, Thomas
    Yoshida, Mizuki
    Koide, Yuichiro
    Umeyama, Yoshiko
    di Pietro, Alessandra
    Uemura, Hirotsugu
    [J]. INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 2022, 27 (02) : 383 - 395
  • [3] Avelumab first-line maintenance plus best supportive care (BSC) vs. BSC alone for advanced urothelial carcinoma: JAVELIN Bladder 100 Asian subgroup analysis
    Lee, Jae-Lyun
    Desai, Chirag
    Park, Se Hoon
    Tsuchiya, Norihiko
    Su, Po-Jung
    Chan, Timothy Tim Wai
    Gurney, Howard
    Gao, Seasea
    Wang, Jing
    Sandner, Robin
    di Pietro, Alessandra
    Eto, Masatoshi
    [J]. UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 2023, 41 (05) : 256.e17 - 256.e25
  • [4] Maintenance avelumab plus best supportive care (BSC) versus BSC alone after platinum-based first-line (1L) chemotherapy in advanced urothelial carcinoma (UC): JAVELIN Bladder 100 phase III interim analysis.
    Powles, Thomas
    Park, Se Hoon
    Voog, Eric
    Caserta, Claudia
    Valderrama, B. P.
    Gurney, Howard
    Kalofonos, Haralabos
    Radulovic, Sinisa
    Demey, Wim
    Ullen, Anders
    Loriot, Yohann
    Sridhar, Srikala S.
    Tsuchiya, Norihiko
    Kopyltsov, Evgeny
    Sternberg, Cora N.
    Bellmunt, Joaquim
    Aragon-Ching, Jeanny B.
    Petrylak, Daniel Peter
    di Pietro, Alessandra
    Grivas, Petros
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (18)
  • [5] Avelumab first-line maintenance plus best supportive care vs best supportive care alone for advanced urothelial carcinoma: JAVELIN Bladder 100 subgroup analysis based on duration and cycles of first-line chemotherapy
    Gurney, Howard
    Loriot, Yohann
    Powles, Thomas
    Duran, Climent Miguel
    Sridhar, Srikala
    Bellmunt, Joaquim
    Petrylak, Daniel
    Wang, Jing
    Costa, Nuno
    Laliberte, Robert
    Di Pietro, Alessandra
    Grivas, Petros
    Sternberg, Cora
    [J]. ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 2021, 17 : 46 - 46
  • [6] Avelumab first-line (1L) maintenance plus best supportive care (BSC) versus BSC alone in Asian patients with advanced urothelial carcinoma (UC): JAVELIN Bladder 100 subgroup analysis.
    Eto, Masatoshi
    Lee, Jae-Lyun
    Park, Se Hoon
    Tsuchiya, Norihiko
    Su, Po-Jung
    Chan, T. W.
    Desai, Chirag Jyotiker
    Di Pietro, Alessandra
    Wang, Jing
    Laliberte, Robert J.
    Gao, Seasea
    Gurney, Howard
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (06)
  • [7] Avelumab first-line maintenance plus best supportive care vs best supportive care alone for advanced urothelial carcinoma: JAVELIN Bladder 100 subgroup analysis based on duration and cycles of first-line chemotherapy
    Powles, Thomas
    Loriot, Yohann
    Duran, Miguel A. Climent
    Sridhar, Srikala
    Bellmunt, Joaquim
    Petrylak, Daniel P.
    Wang, Jing
    Costa, Nuno
    Laliberte, Robert
    di Pietro, Alessandra
    Grivas, Petros
    Sternberg, Cora N.
    [J]. ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 2021, 17 : 132 - 133
  • [8] Patient-reported outcomes (PROs) from JAVELIN Bladder 100: Avelumab first-line (1L) maintenance plus best supportive care (BSC) vs BSC alone for advanced urothelial carcinoma (UC)
    Powles, T. B.
    Kopyltsov, E.
    Su, P-J.
    Parnis, F. X.
    Park, S. H.
    Yamamoto, Y.
    Fong, P. C.
    Tournigand, C.
    Duran, M. A. Climent
    Bamias, A.
    Caserta, C.
    Chang, J.
    Yan, E.
    di Pietro, A.
    Wang, J.
    Grivas, P.
    [J]. ANNALS OF ONCOLOGY, 2020, 31 : S578 - S579
  • [9] Avelumab first-line (1L) maintenance plus best supportive care (BSC) vs BSC alone with 1L chemotherapy (CTx) for advanced urothelial carcinoma (UC): Subgroup analyses from JAVELIN Bladder 100
    Grivas, P.
    Park, S. H.
    Voog, E.
    Caserta, C.
    Perez Valderrama, B.
    Gurney, H.
    Kalofonos, H.
    Radulovic, S.
    Demey, W.
    Ullen, A.
    Loriot, Y.
    Sridhar, S. S.
    Tsuchiya, N.
    Kopyltsov, E.
    Gupta, S.
    Huang, B.
    Costa, N.
    Blake-Haskins, J. A.
    di Pietro, A.
    Powles, T. B.
    [J]. ANNALS OF ONCOLOGY, 2020, 31 : S555 - S556
  • [10] Avelumab first-line maintenance plus best supportive care vs best supportive care alone for advanced urothelial carcinoma not progressed with first-line chemotherapy: prespecified subgroup analyses from JAVELIN Bladder 100
    Lumba, Sumit
    Grivas, Petros
    Park, Se Hoon
    Voog, Eric
    Caserta, Claudia
    Valderrama, Begona P.
    Gurney, Howard
    Kalofonos, Haralabos
    Radulovic, Sinisa
    Demey, Wim
    Ullen, Andres
    Loriot, Yohann
    Sridhar, Srikala S.
    Tsuchiya, Norihiko
    Kopyltsov, Evgeny
    Gupta, Shilpa
    Huang, Bo
    Costa, Nuno
    Blake-Haskins, John A.
    di Pietro, Alessandra
    Powles, Thomas
    [J]. ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 2021, 17 : 42 - 43