Dromedary Camels and the Transmission of Middle East Respiratory Syndrome Coronavirus (MERS-CoV)

被引:81
|
作者
Hemida, M. G. [1 ,2 ]
Elmoslemany, A. [3 ,4 ]
Al-Hizab, F. [5 ]
Alnaeem, A. [3 ]
Almathen, F. [6 ]
Faye, B. [7 ]
Chu, D. K. W. [8 ]
Perera, R. A. P. M. [8 ]
Peiris, M. [8 ]
机构
[1] King Faisal Univ, Coll Vet Med & Anim Resources, Dept Microbiol & Parasitol, Al Hasa 4000, Saudi Arabia
[2] Kafrelsheikh Univ, Fac Vet Med, Dept Virol, Kafrelsheikh, Egypt
[3] King Faisal Univ, Coll Vet Med & Anim Resources, Dept Clin Studies, Al Hsa, Saudi Arabia
[4] Kafrelsheikh Univ, Fac Vet Med, Hyg & Prevent Med Dept, Kafrelsheikh, Egypt
[5] King Faisal Univ, Coll Vet Med & Anim Resources, Dept Pathol, Al Hsa, Saudi Arabia
[6] King Faisal Univ, Coll Vet Med & Anim Resources, Dept Publ Hlth & Anim Welf, Al Hsa, Saudi Arabia
[7] FAO Consultant, Ctr Agr Project, Camel Project UTF SAU SAU 044, Al Kharj, Saudi Arabia
[8] Univ Hong Kong, Sch Publ Hlth, Hong Kong, Hong Kong, Peoples R China
关键词
MERS-CoV; coronavirus; zoonosis; human; dromedary camels; transmission; SAUDI-ARABIA; NEUTRALIZING ANTIBODIES; INFECTED CAMELS; MILK; LIVESTOCK; DIARRHEA; QATAR; BAT; REPLICATION; SEPTEMBER;
D O I
10.1111/tbed.12401
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Middle East respiratory syndrome coronavirus (MERS-CoV) is an existential threat to global public health. The virus has been repeatedly detected in dromedary camels (Camelus dromedarius). Adult animals in many countries in the Middle East as well as in North and East Africa showed high (> 90%) seroprevalence to the virus. Middle East respiratory syndrome coronavirus isolated from dromedaries is genetically and phenotypically similar to viruses from humans. We summarize current understanding of the ecology of MERS-CoV in animals and transmission at the animal-human interface. We review aspects of husbandry, animal movements and trade and the use and consumption of camel dairy and meat products in the Middle East that may be relevant to the epidemiology of MERS. We also highlight the gaps in understanding the transmission of this virus in animals and from animals to humans.
引用
收藏
页码:344 / 353
页数:10
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