Primary Carcinoma of the Fallopian Tube: A Review of a Single Institution Experience of 8 Cases

被引:7
|
作者
Nanaiah, Shakuntala P. [1 ]
Rathod, Praveen S. [1 ]
Rajkumar, Namrata N. [2 ]
Kundargi, Rajshekar [1 ]
Subbian, Anbukkani [1 ]
Ramachandra, Pallavi V. [1 ]
Krishnappa, Shobha [1 ]
Narayan, Abhilasha [1 ]
Devi, Uma K. [1 ]
Uttamchand, Bafna D. [1 ]
机构
[1] Kidwai Mem Inst Oncol, Dept Gynaecol Oncol, Bengaluru 560030, Karnataka, India
[2] Kidwai Mem Inst Oncol, Dept Pathol, Bengaluru 560030, Karnataka, India
来源
关键词
MULTIINSTITUTIONAL RETROSPECTIVE ANALYSIS; EPITHELIAL OVARIAN-CANCER; PROGNOSTIC-FACTORS; SURVIVAL; ADENOCARCINOMA; PATHOGENESIS; ORIGIN;
D O I
10.1155/2014/630731
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Aims and Objectives. To evaluate the clinicopathologic features, response to cytoreductive surgery and adjuvant platinum-based chemotherapy with or without paclitaxel. Materials and Methods. A retrospective observational study of 8 women with a histopathologic diagnosis of primary fallopian tube carcinoma (PFTC) from January 2000 to February 2013. Results. 4/8 (50%) of the women were in the early stage and an intraoperative frozen section was 100% effective in identifying fallopian tube carcinoma and then a staging laparotomy was performed. All 4/8 cases in the early stage had received and responded to single agent carboplatin and all are alive without clinical, radiological, or biochemical evidence of recurrence at the end of 2 years and the longest survivor has completed 13 years. Primary optimal cytoreductive surgery was achievable in 3/4 (75%) in advanced disease. All showed response to adjuvant paclitaxel and carboplatin (T + C), but all had succumbed to the disease following recurrence with mean progression free survival of 19 months (range 15-21 months) and mean overall survival of 27 months (range 22-36 months). Conclusion. The pivotal role played by a frozen section in diagnosing PFTC which is rare needs to be reemphasized, therefore justifying a primary staging laparotomy in an early stage. Prolonged survival observed in this group following an optimum tailored adjuvant single agent carboplatin is worth noting.
引用
收藏
页数:7
相关论文
共 50 条
  • [1] Primary Fallopian Tube Carcinoma: A Single-Institution Experience of 101 Cases A Retrospective Study
    Bao, Lingjie
    Ding, Yan
    Cai, QingQing
    Ning, Yan
    Hu, Weiguo
    Xue, Xiaohong
    Sun, Hong
    Hua, Keqin
    Zhou, Xianrong
    Yi, Xiaofang
    [J]. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2016, 26 (03) : 424 - 430
  • [2] Clinicopathological features of primary fallopian tube carcinoma: a single institution experience
    Papadimitriou, C. A.
    Markaki, S.
    Lianos, E.
    Peitsidis, P.
    Vourli, G.
    Nikitas, N.
    Vlachos, G.
    Rodolakis, A.
    Antsaklis, A.
    Dimopoulos, M. A.
    [J]. EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, 2009, 30 (04) : 389 - 395
  • [3] PRIMARY CARCINOMA OF FALLOPIAN TUBE - A REPORT OF 8 CASES
    ROSS, WM
    WARD, CV
    LINDSAY, CC
    [J]. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1962, 83 (04) : 425 - &
  • [4] Clinical characteristics of primary Fallopian tube carcinoma: A single-institution retrospective study of 57 cases
    Ma, Zhihua
    Gao, Li
    Li, Han
    Li, Jie
    Zhang, Guanjun
    Xue, Yan
    [J]. INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 2021, 153 (03) : 405 - 411
  • [5] PRIMARY-CARCINOMA OF FALLOPIAN-TUBE - EXPERIENCE OF 6 CASES
    BORGHI, L
    BALLOTTA, MR
    BIANCHINI, E
    GARAVELLO, B
    BONONI, A
    FORTINI, RM
    [J]. EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 1994, 57 (03): : 161 - 166
  • [6] Paclitaxel-and platinum-based postoperative chemotherapy for primary fallopian tube carcinoma: A single institution experience
    Papadimitriou, Christos A.
    Peitsidis, Panagiotis
    Bozas, George
    Grimani, Irene
    Vlahos, George
    Rodolakis, Alexandros
    Lianos, Evangelos
    Bamias, Aristotelis
    Lainakis, George
    Dimopoulos, Meletios-A.
    [J]. ONCOLOGY, 2008, 75 (1-2) : 42 - 48
  • [7] Two cases of primary carcinoma of the fallopian tube
    Baker, JO
    Blais, A
    [J]. CANADIAN MEDICAL ASSOCIATION JOURNAL, 1942, 46 : 67 - 68
  • [8] PRIMARY CARCINOMA OF FALLOPIAN TUBE - REPORT OF 3 CASES AND REVIEW OF LITERATURE
    CRIST, T
    PALUMBO, L
    SHINGLETON, HM
    [J]. SOUTHERN MEDICAL JOURNAL, 1968, 61 (03) : 311 - +
  • [9] Primary Carcinoma of the Fallopian Tube: Report of Two Cases with Literature Review
    Jeung, In Cheul
    Lee, Yong Seok
    Lee, Hae Nam
    Park, Eun Kyung
    [J]. CANCER RESEARCH AND TREATMENT, 2009, 41 (02): : 113 - 116
  • [10] Primary fallopian tube carcinoma: the Queensland experience
    Obermair, A
    Taylor, KH
    Janda, M
    Nicklin, JL
    Crandon, AJ
    Perrin, L
    [J]. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2001, 11 (01) : 69 - 72