Syntheses of Bioactive Natural Products and Natural-Product-Like Compounds Based on Their Key Structural Units

被引：12

作者：

Zhang, Hongbin ^{[1
]}

机构：

[1] Yunnan Univ, Minist Educ, Sch Chem Sci & Technol, Key Lab Med Chem Nat Resource, Kunming 650091, Yunnan, Peoples R China

来源：

SYNLETT | 2014年 / 25卷 / 14期

关键词：

key structural unit; sequential reactions; total synthesis; natural products; natural-product-like compounds; ENANTIOSELECTIVE MICHAEL ADDITIONS; CATALYTIC ASYMMETRIC-SYNTHESIS; SIMPLE INDOLE ALKALOIDS; CONJUGATE ADDITION; 1,3-DICARBONYL COMPOUNDS; ALLYLIC ALKYLATION; FORMAL SYNTHESIS; RECENT PROGRESS; ARYLATION; ERYTHRINA;

D O I：

10.1055/s-0033-1338641

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This account describes our recent efforts toward the syntheses of natural products and natural-product-like compounds. Developing new strategies based on the key structural unit present in a target molecule is our main focus in the journey leading to the total synthesis of natural products. 1 Introduction 2 Synthesis of Podophyllotoxin 3 Synthesis of Mesembrine 4 Synthesis of Hexahydropyrroloindole Alkaloids 5 Total Synthesis of Stenine 6 Synthesis of Brazilide A, Brazilin, and Aza-Brazilins 7 Synthesis of Important Structural Units Present in Natural Products and Pharmaceuticals 8 Summary

引用

页码：1953 / 1970

页数：18

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