Synthesis of poly acrylic acid modified silver nanoparticles and their antimicrobial activities

被引:52
|
作者
Ni, Zhihui [1 ]
Wang, Zhihua [2 ]
Sun, Lei [1 ]
Li, Binjie [3 ]
Zhao, Yanbao [1 ]
机构
[1] Henan Univ, Key Lab Special Funct Mat, Minist Educ, Kaifeng 475004, Peoples R China
[2] Henan Univ, Inst Environm & Analyt Sci, Coll Chem & Chem Engn, Kaifeng 475004, Peoples R China
[3] Henan Univ, Key Lab Cellular & Mol Immunol, Kaifeng 475004, Peoples R China
基金
中国国家自然科学基金; 中国博士后科学基金;
关键词
Synthesis; Poly acrylic add; Silver nanoparticles; Antimicrobial property; ANTIBACTERIAL ACTIVITY; NANOCOMPOSITES; SIZE;
D O I
10.1016/j.msec.2014.04.059
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
Poly acrylic acid modified silver (Ag/PAA) nanoparticles (NPs) have been successfully synthesized in the aqueous solution by using tannic acid as a reductant. The structure, morphology and composition of Ag/PAA NPs were characterized by various techniques such as X-ray powder diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), ultraviolet-visible absorption spectroscopy (UV-vis) and thermogravimetry analysis (TGA). The results show that PAA/Ag NPs have a quasi-ball shape with an average diameter of 10 nm and exhibit well crystalline, and the reaction conditions have some effect on products morphology and size distribution. In addition, the as-synthesized Ag/PAA NPs antimicrobial activities against Escherichia coli (E. coli), Pseudomonas aeruginosa (P. aeruginosa) and Staphylococcus aureus (S. aureus) were evaluated by the methods of broth dilution, cup diffusion, optical density (OD600) and electron microscopy observation. The as-synthesized Ag/PAA NPs exhibit excellent antibacterial activity. The antimicrobial mechanism may be attributed to the damaging of bacterial cell membrane and causing leakage of cytoplasm. (C) 2014 Elsevier B.V. All rights reserved.
引用
收藏
页码:249 / 254
页数:6
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