Early Clinical Results of a Novel Anti-CD20 Chimeric Antigen Receptor (CAR)-T Cell Therapy for B-Cell NHL Patients Who Are Relapsed/Resistant Following CD19 CAR-T Therapy

被引：4
|
作者：
Ye, Shiguang
Huang, Jiaqi
Zhu, Shigui
Yao, Xin
Zhou, Lili
Zhu, Judy
Zheng, Chengxiao
Chen, Shiyi
Lan, Liping
Chen, Shicheng
Wei, Yutian
Shu, Wangqin
Ye, Chen
Zhang, Dan
Wang, Rirfei
Hong, Yi
Ren, Jiaqiang
Zhang, Li
Zhang, Wenjun
Tang, Xiaochen
Wang, Junbang
Liu, Jie
Humphries, Michael
Li, Ping
Yao, Yihong
Liang, Aibin
机构：
来源：
BLOOD | 2020年 / 136卷
关键词：
D O I：
10.1182/blood-2020-138538
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页数：3
相关论文
共 50 条
  • [1] Safety and efficacy of a novel anti-CD20 chimeric antigen receptor (CAR)-T cell therapy in relapsed/refractory (r/r) B-cell non-Hodgkin lymphoma (B-NHL) patients after failing CD19 CAR-T therapy.
    Liang, Aibin
    Ye, Shiguang
    Li, Ping
    Huang, Jiaqi
    Zhu, Shigui
    Yao, Xin
    Zhou, Lili
    Xu, Yangyang
    Zhu, Judy
    Zheng, Chengxiao
    Chen, Shiyi
    Lan, Liping
    Lv, Xiaoteng
    Wei, Yutian
    Humphries, Michael
    Yao, Yihong
    JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (15)
  • [2] Two-Year Follow-up Results of C-CAR066, a Novel Anti-CD20 Chimeric Antigen Receptor Cell Therapy (CAR-T) in Relapsed or Refractory (r/r) Large B-Cell Lymphoma (LBCL) Patients after Failure of CD19 CAR-T Therapy
    Li, Ping
    Liu, Wei
    Ye, Shiguang
    Zhou, Lili
    Zhu, Judy
    Huang, Jiaqi
    Li, Jing
    Zhu, Shigui
    Zheng, Chengxiao
    Zhu, Kevin
    Yao, Xin
    Wan, Hui
    Yao, Yihong
    Liang, Aibin
    Zou, Dehui
    BLOOD, 2023, 142
  • [3] Developing a Novel Anti-CD19/CD20 Bi-Specific Chimeric Antigen Receptor T (CAR-T) Cell Therapy for Relapsed/Refractory (r/r) B-Cell NHL
    Zhou, Lili
    Huang, Jiaqi
    Zhu, Shigui
    Yao, Xin
    Ye, Shiguang
    Zhu, Judy
    Zheng, Chengxiao
    Chen, Shiyi
    Li, Yanfeng
    Lan, Liping
    Chen, Shicheng
    Guo, Lin
    Zhang, Qingsong
    Zheng, Jiangqin
    Wang, Rirfei
    Hong, Yi
    Ren, Jiaqiang
    Zhang, Li
    Zhang, Wenjun
    Tang, Xiaochen
    Wang, Junbang
    Liu, Jie
    Humphries, Michael
    Li, Ping
    Yao, Yihong
    Liang, Aibin
    BLOOD, 2020, 136
  • [4] C-CAR066, a novel fully human anti-CD20 CAR-T therapy for relapsed or refractory large B-cell lymphoma after failure of anti-CD19 CAR-T therapy: A phase I clinical study
    Li, Ping
    Liu, Wei
    Zhou, Lili
    Ye, Shiguang
    Zhu, Dan
    Huang, Jiaqi
    Li, Jing
    Zheng, Chengxiao
    Zhu, Shigui
    Yao, Xin
    Zhu, Kevin
    Yao, Yihong
    Qiu, Lugui
    Liang, Aibin
    Zou, Dehui
    AMERICAN JOURNAL OF HEMATOLOGY, 2024, 99 (12) : 2306 - 2312
  • [5] Humanized CD19 CAR-T cells in relapsed/refractory B-ALL patients who relapsed after or failed murine CD19 CAR-T therapy
    Lihong An
    Yuehui Lin
    Biping Deng
    Zhichao Yin
    Defeng Zhao
    Zhuojun Ling
    Tong Wu
    Yongqiang Zhao
    Alex H. Chang
    Chunrong Tong
    Shuangyou Liu
    BMC Cancer, 22
  • [6] A CD19/CD20-Directed Bispecific CAR-T Cell Therapy in Relapsed or Refractory Aggressive B-Cell Non-Hodgkin Lymphoma (NHL)
    Larson, Sarah M.
    Chen, Yvonne Y.
    Johnston, Jim
    Roy, Sylvain
    Patel, Pinakin
    Benjamin, Jonathan E.
    BLOOD, 2023, 142
  • [7] CD19/CD22 CAR-T Cell Cocktail Therapy Following Autologous Transplantation in Patients with Relapsed/Refractory B-Cell Lymphomas
    Cao, Yang
    Xiao, Yi
    Wang, Na
    Wang, Gaoxiang
    Zhou, Xiaoxi
    Huang, Liang
    Chen, Liting
    Xiao, Min
    Zhang, Tongcun
    Zhang, Yicheng
    Zhou, Jianfeng
    BLOOD, 2020, 136
  • [8] Combating antigen escape with CD19/CD20 bispecific CAR-T cell therapy
    Zah, Eugenia
    Lin, Meng-Yin
    Jensen, Michael C.
    Silva-Benedict, Anne
    Chen, Yvonne Y.
    CANCER IMMUNOLOGY RESEARCH, 2017, 5 (03)
  • [9] CD19 CAR-T Cell Therapy in Children with Relapsed and Refractory B-ALL
    Molostova, Olga
    Shelikhova, Larisa
    Muzalevsky, Yakov
    Kazachenok, Alexey
    Khismatullina, Rimma
    Abugova, Julia
    Kurnikova, Elena
    Trakhtman, Pavel
    Pershin, Dmitry
    Zubachenko, Viktoria
    Fadeeva, Maria
    Popov, Alexander M.
    Illarionova, Olga
    Miakova, Natalia
    Litvinov, Dmitry
    Novichkova, Galina
    Maschan, Alexey
    Maschan, Michael
    BLOOD, 2021, 138
  • [10] Efficacy and safety of humanized CD19 CAR-T as a salvage therapy for recurrent CNSL of B-ALL following murine CD19 CAR-T cell therapy
    Li, Xin
    Liu, Mei-Jing
    Mou, Nan
    Yang, Zhen-Xing
    Wang, Jia
    Mu, Juan
    Zhu, Hai-Bo
    Deng, Qi
    ONCOLOGY LETTERS, 2021, 22 (05)
12345