Anti-Inflammatory Activity of Centella Asiatica Mediated Silver Nanoparticles

Introduction: Inflammation is the body's main reaction to an illness or injury, and it is vital to our immunity. Because of the increasing prevalence of pain and pain-related disorders, as well as other health treatment complexities, it is important to be mindful of the anti-inflammatory medications available on the market. Furthermore, nonsteroidal anti-inflammatory medications have been related to side effects including stomach pain, heartburn, and ulcers. So, this study deals with the anti-inflammatory activity of Centella mediated silver nanoparticles Materials and methods: Collection of Centella asiatica extract then 1 g of Centella asiatica, leaf powder was dissolved in distilled water and boiled for 5-10 min at 60-70C. The solutions were then filtered using Whatman No. 1 filter paper. The filtered extract was collected, synthesis of silver nanoparticles using an herbal formulation, and to finalize the anti-inflammatory activity of silver nanoparticles. Result: Anti-inflammatory activity of silver nanoparticles show an incremental pattern with increase in concentration, where percentage of inhibition is high at 50 mu l. Its activity increases with increase in dosage. Conclusion: This study thus provides a strong base for understanding the anti-inflammatory activity of silver nanoparticles.