CAR T Cells Express CD40L and Activates Human Dendritic Cells

被引:0
|
作者
Karlsson, Hannah [1 ]
Gustafsson, Wictor [1 ]
Stromberg, Ulla Olsson [2 ,3 ]
Savoldo, Barbara [4 ]
Dotti, Gianpietro [4 ]
Loskog, Angelica [1 ]
机构
[1] Uppsala Univ, Dept Immunol Genet & Pathol, Uppsala, Sweden
[2] Uppsala Univ, Dept Med Sci, Uppsala, Sweden
[3] Univ Uppsala Hosp, Sect Hematol, Uppsala, Sweden
[4] Baylor Coll Med, Ctr Cell & Gene Therapy, Houston, TX 77030 USA
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
162
引用
收藏
页码:S61 / S61
页数:1
相关论文
共 50 条
  • [1] Human dendritic cells activated by TSLP and CD40L induce proallergic cytotoxic T cells
    Gilliet, M
    Soumelis, V
    Watanabe, N
    Hanabuchi, S
    Antonenko, S
    de Waal-Malefyt, R
    Liu, YJ
    JOURNAL OF EXPERIMENTAL MEDICINE, 2003, 197 (08): : 1059 - 1063
  • [2] The role of CD40 and CD154/CD40L in dendritic cells
    Ma, Daphne Y.
    Clark, Edward A.
    SEMINARS IN IMMUNOLOGY, 2009, 21 (05) : 265 - 272
  • [3] CD40L-Tri, a novel formulation of recombinant human CD40L that effectively activates B cells
    Naito, Masayasu
    Hainz, Ursula
    Burkhardt, Ute E.
    Fu, Buyin
    Ahove, Deborah
    Stevenson, Kristen E.
    Rajasagi, Mohini
    Zhu, Baogong
    Alonso, Anselmo
    Witten, Elizabeth
    Matsuoka, Ken-ichi
    Neuberg, Donna
    Duke-Cohan, Jonathan S.
    Wu, Catherine J.
    Freeman, Gordon J.
    CANCER IMMUNOLOGY IMMUNOTHERAPY, 2013, 62 (02) : 347 - 357
  • [4] CD40L-Tri, a novel formulation of recombinant human CD40L that effectively activates B cells
    Masayasu Naito
    Ursula Hainz
    Ute E. Burkhardt
    Buyin Fu
    Deborah Ahove
    Kristen E. Stevenson
    Mohini Rajasagi
    Baogong Zhu
    Anselmo Alonso
    Elizabeth Witten
    Ken-ichi Matsuoka
    Donna Neuberg
    Jonathan S. Duke-Cohan
    Catherine J. Wu
    Gordon J. Freeman
    Cancer Immunology, Immunotherapy, 2013, 62 : 347 - 357
  • [5] Chronic inflammation in atherosclerosis-The CD40L/CD40 axis belongs to dendritic cells and T cells, not platelets
    Langer, Harald F.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2022, 20 (01) : 3 - 5
  • [6] INTRATUMORAL TREATMENT WITH DENDRITIC CELLS ENGINEREED TO EXPRESS CD40L OR CD40L AND IL-2 INDUCES INHIBITION OF SUBCUTANEOUS HEPATOCELLULAR TUMOR GROWTH IN MICE
    Vogt, A.
    Demmer, W.
    Caselmann, W. H.
    Sauerbruch, T.
    Gonzalez-Carmona, M. A.
    JOURNAL OF HEPATOLOGY, 2009, 50 : S122 - S123
  • [7] INTRATUMORAL TREATMENT WITH DENDRITIC CELLS ENGINEREED TO EXPRESS CD40L OR CD40L AND IL-2 INDUCES INHIBITION OF SUBCUTANEOUS HEPATOCELLULAR TUMOR GROWTH IN MICE
    Gonzalez-Carmona, Maria A.
    Vogt, Annabelle
    Demmer, Wolfram
    Sauerbruch, Tilman
    Caselmann, Wolfgang H.
    HEPATOLOGY, 2008, 48 (04) : 1114A - 1115A
  • [8] Regulation of CD40L Transgene Expression in Human CAR-T Cells Using FDA Approved Ligands
    Weisman, Elizabeth
    Brideau, Emily
    Elpek, Kutlu
    Fleury, Michelle
    Heller, Scott
    Reardon, Christopher
    Schebesta, Michael
    Sethi, Dhruv
    Sun, Dexue
    Tran, Karen
    Briskin, Michael
    Gori, Jennifer L.
    Richardson, Celeste
    Suri, Vipin
    Shamah, Steven
    MOLECULAR THERAPY, 2019, 27 (04) : 266 - 266
  • [9] CD40L Expression Allows CD8+ T Cells to Promote Their Own Expansion and Differentiation through Dendritic Cells
    Tay, Neil Q.
    Lee, Debbie C. P.
    Chua, Yen Leong
    Prabhu, Nayana
    Gascoigne, Nicholas R. J.
    Kemeny, David M.
    FRONTIERS IN IMMUNOLOGY, 2017, 8
  • [10] Immune Check Point CD40-CD40L Activates Dendritic and Effector Cells Against Human Renal Carcinoma Cells
    Hillebrand, Regina M.
    Vogt, Annabelle
    Strassburg, Christian P.
    Gonzalez-Carmona, Maria A.
    Schmidt-Wolf, Ingo G. H.
    ANTICANCER RESEARCH, 2019, 39 (09) : 4643 - 4652