Intelligence and professional career in young adults treated early for phenylketonuria

被引：21
|
作者：
Schmidt, H [1 ]
Burgard, P [1 ]
Pietz, J [1 ]
Rupp, A [1 ]
机构：
[1] UNIV HEIDELBERG,DEPT PAEDIAT NEUROL,D-69120 HEIDELBERG,GERMANY
来源：
EUROPEAN JOURNAL OF PEDIATRICS | 1996年 / 155卷
关键词：
phenylketonuria; intelligence; education; professional career; phenylalanine control;
D O I：
10.1007/PL00014262
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
The intellectual status and professional careers of 51 young adults with phenylketonuria whose treatment started before 3 months of age are described. Their mean IQ was 97 (SD = 16). Of the IQs, 4% were more than 2 SD below the norm. The distribution of types of schooling of the patients was comparable to that in the German population. The professional careers of nearly all the patients were according to their educational level. Within the sample the outcome was significantly correlated with phenylalanine (Phe) control, even when the patients' social background was statistically taken into account. The main influence of Phe on intelligence seems to oi:cur during the first decade of life since IQ data remain stable even after Phe levels increased during adolescence.
引用
收藏
页码：S97 / S100
页数：4
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