Nonstructural protein 5A/P32 deletion after failure of ledipasvir/sofosbuvir in hepatitis C virus genotype 1b infection

被引:17
|
作者
Doi, Akira [1 ]
Hikita, Hayato [1 ]
Sakamori, Ryotaro [1 ]
Tahata, Yuki [1 ]
Kai, Yugo [1 ]
Yamada, Ryoko [1 ]
Yakushijin, Takayuki [2 ]
Mita, Eiji [3 ]
Ohkawa, Kazuyoshi [4 ]
Imai, Yasuharu [5 ]
Furuta, Kunimaro [1 ]
Kodama, Takahiro [1 ]
Tatsumi, Tomohide [1 ]
Takehara, Tetsuo [1 ]
机构
[1] Osaka Univ, Dept Gastroenterol & Hepatol, Grad Sch Med, 2-2 Yamadaoka, Suita, Osaka 5650871, Japan
[2] Osaka Gen Med Ctr, Dept Gastroenterol & Hepatol, Osaka, Japan
[3] Osaka Natl Hosp, Natl Hosp Org, Dept Gastroenterol & Hepatol, Osaka, Japan
[4] Osaka Int Canc Inst, Dept Hepatobiliary & Pancreat Oncol, Osaka, Japan
[5] Ikeda Municipal Hosp, Ikeda, Osaka, Japan
关键词
D O I
10.1002/hep.29836
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
[No abstract available]
引用
收藏
页码:380 / 383
页数:4
相关论文
共 50 条
  • [1] Sofosbuvir, pegylated interferon, and ribavirin for retreatment of hepatitis C virus genotype 1b following sofosbuvir and ledipasvir failure
    Kalal, Chetan
    Shukla, Akash
    Mohanka, Ravi
    Vora, Mihir
    Patel, Priyesh
    Shah, Samir
    HEPATOLOGY, 2018, 67 (05) : 2049 - 2050
  • [2] Duplication of V3 domain in nonstructural 5A protein of hepatitis C virus genotype 1b
    Veillon, P
    Redureau, J
    Coueffic, B
    Subra, JF
    Causse, X
    Gaudy, C
    Payan, C
    Lunel-fabiani, F
    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2004, 24 : S239 - S239
  • [3] Role of ledipasvir/sofosbuvir combination for genotype 1 hepatitis C virus infection
    Sundaram, Vinay
    Kowdley, Kris V.
    HEPATIC MEDICINE-EVIDENCE AND RESEARCH, 2016, 8 : 75 - 80
  • [4] Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection
    Enomoto, N
    Sakuma, I
    Asahina, Y
    Kurosaki, M
    Murakami, T
    Yamamoto, C
    Ogura, Y
    Izumi, N
    Marumo, F
    Sato, C
    NEW ENGLAND JOURNAL OF MEDICINE, 1996, 334 (02): : 77 - 81
  • [5] Insertion of a new V3-like domain in nonstructural 5A protein of hepatitis C virus genotype 1B
    Veillon, P
    Lunel, F
    Redureau, J
    Coeffic, B
    Subra, JF
    Causse, X
    Dubois, P
    Gaudy, C
    Payan, C
    JOURNAL OF HEPATOLOGY, 2005, 42 : 162 - 162
  • [6] The nonstructural 5A protein of hepatitis C virus genotype 1b does not contain an interferon sensitivity-determining region
    Brillet, Rozenn
    Penin, Francois
    Hezode, Christophe
    Chouteau, Philippe
    Dhumeaux, Daniel
    Pawlotsky, Jean-Michel
    JOURNAL OF INFECTIOUS DISEASES, 2007, 195 (03): : 432 - 441
  • [7] Interferon resistance of hepatitis C virus genotype 1b: Relationship to nonstructural 5A gene quasispecies mutations
    Pawlotsky, JM
    Germanidis, G
    Neumann, AU
    Pellerin, M
    Frainais, PO
    Dhumeaux, D
    JOURNAL OF VIROLOGY, 1998, 72 (04) : 2795 - 2805
  • [8] The nonstructural 5A (NS5A) protein of hepatitis C virus genotype 1B does not contain an "interferon sensitivity determining region"
    Brillet, Rozenn
    Penin, Francois
    Hezode, Christophe
    Chouteau, Philippe
    Dhumeaux, Daniel
    Pawlotsky, Jean-Michel
    HEPATOLOGY, 2006, 44 (04) : 313A - 313A
  • [9] Functional comparison of the antagonism of hepatitis C virus genotype 1b and 2a nonstructural protein 5a to interferon antiviral activity
    Tsai, Y.
    Hwang, L.
    JOURNAL OF CLINICAL VIROLOGY, 2006, 36 : S114 - S114
  • [10] Ledipasvir and sofosbuvir:Interferon free therapy for hepatitis C virus genotype 1 infection
    Yasir Waheed
    World Journal of Virology, 2015, (01) : 33 - 35