Chemical Constituents from the Aerial Parts of Artemisia minor

被引：53
|
作者：
He, Zhi-Zhou [1 ]
Yan, Ju-Fang [1 ]
Song, Zhi-Jun [1 ]
Ye, Fei [1 ]
Liao, Xun [1 ]
Peng, Shu-Lin [1 ]
Ding, Li-Sheng [1 ]
机构：
[1] Chinese Acad Sci, Chengdu Inst Biol, Natl Engn Res Ctr Nat Med, Chengdu 610041, Peoples R China
来源：
JOURNAL OF NATURAL PRODUCTS | 2009年 / 72卷 / 06期
关键词：
ARTEMINOLIDE; TRANSFERASE; COUMARIN; ASSAY;
D O I：
10.1021/np800643n
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Four new compounds including three bicoumarins, arteminorins A-C (1-3). and one neolignan, arteminorin D (4), together with 31 known ones were isolated from the aerial parts of Artemisia minor. Their structures were established on the basis of spectroscopic data and comparison with those of the related known compounds. Ethyl caffeate (27) showed in vitro cytotoxicity against the HepG2 cancer cell line. Arteminorin C (3) and luteolin (19) showed inhibitory activity on xanthine oxidase (XOD), and caffeic acid (28) exhibited inhibitory activity on protein tyrosine phosphatase 1B (PTP1B).
引用
收藏
页码：1198 / 1201
页数：4
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