Applying a PrEP Continuum of Care for Men Who Have Sex With Men in Atlanta, Georgia

被引：233
|
作者：
Kelley, Colleen F. [1 ,2 ]
Kahle, Erin [2 ]
Siegler, Aaron [2 ]
Sanchez, Travis [2 ]
del Rio, Carlos [1 ,3 ]
Sullivan, Patrick S. [2 ]
Rosenberg, Eli S. [2 ]
机构：
[1] Emory Univ, Sch Med, Div Infect Dis, Dept Med, Atlanta, GA 30322 USA
[2] Emory Univ, Rollins Sch Publ Hlth, Dept Epidemiol, Atlanta, GA 30322 USA
[3] Emory Univ, Rollins Sch Publ Hlth, Hubert Dept Global Hlth, Atlanta, GA 30322 USA
来源：
CLINICAL INFECTIOUS DISEASES | 2015年 / 61卷 / 10期
基金：
美国国家卫生研究院;
关键词：
men who have sex with men; pre-exposure prophylaxis; continuum of care; ORAL PREEXPOSURE PROPHYLAXIS; HIV PREVENTION; ANTIRETROVIRAL PROPHYLAXIS; TRANSGENDER WOMEN; WHITE MEN; INFECTION; ACCEPTABILITY; RATES;
D O I：
10.1093/cid/civ664
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Reductions in human immunodeficiency virus (HIV) incidence with pre-exposure prophylaxis (PrEP) for men who have sex with men (MSM) will require significant coverage of those at risk. We propose a simplified framework, similar to the HIV care continuum, to achieve protection with PrEP as follows: 1. At-risk MSM; 2. Awareness of and willingness to take PrEP; 3. Access to healthcare; 4. Receiving a prescription; and 5. Adhering to effective PrEP. We evaluated the PrEP care continuum on an Atlanta cohort of MSM and projected how many MSM might achieve protection from HIV. Even with optimistic estimates, few Atlanta MSM (15%) are projected to achieve protection from HIV with PrEP given the significant barriers described. Each continuum step represents an important point for intervention that could substantially increase the overall effectiveness of PrEP. In addition, novel strategies for PrEP delivery are needed to achieve the necessary effectiveness for Atlanta MSM at risk of HIV.
引用
收藏
页码：1590 / 1597
页数：8
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