Brief Report: Autism Spectrum Disorder: A Comprehensive Survey of Randomized Controlled Trials

被引：7
|
作者：
Tromans, Samuel [1 ,2 ]
Adams, Clive [3 ]
机构：
[1] Leicestershire Partnership NHS Trust, Agnes Unit, Psychiat Intellectual Disabil, Leicester, Leics, England
[2] Univ Leicester, Dept Hlth Sci, 22-28 Princess Rd W, Leicester LE1 6TP, Leics, England
[3] Univ Nottingham, Inst Mental Hlth, Cochrane Schizophrenia Grp, Nottingham, England
来源：
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS | 2018年 / 48卷 / 09期
关键词：
Autism; Autistic; ASD; Randomized; Trials; Survey; CHILDREN;
D O I：
10.1007/s10803-018-3569-y
中图分类号：
B844 [发展心理学（人类心理学）];
学科分类号：
040202 ;
摘要：
We searched the Cochrane Central Register of Controlled Trials to provide an overview of evidence from randomized controlled trials (RCTs) of therapeutic interventions for autism spectrum disorders. From the final survey (529 RCTs), the mean size was 49 participants (standard deviation 50, range 1-479, median 36, mode 40), with a sharp increase in the number of RCTs from 2008. The most frequently evaluated intervention was antipsychotic treatment (n = 44, 3006 participants). The journal with the most RCTs was the Journal of Autism and Developmental Disorders (N = 104). Most trials were small in size, emphasising the need for research groups to collaborate to generate higher quality data with greater applicability to clinical practice.
引用
收藏
页码：3228 / 3232
页数：5
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