ELECTROPHYSIOLOGICAL ANALYSES OF MUTANTS OF THE HUMAN VOLTAGE-GATED SODIUM CHANNEL NAv1.9 THAT CAUSE PAIN DISORDERS BY ESTABLISHING A HETEROLOGOUS EXPRESSION SYSTEM

被引：1
|
作者：
Zhou, Xi [1 ]
Xiao, Zhen [1 ]
Xu, Yan [1 ]
Zhang, Yunxiao [1 ]
Tang, Dongfang [1 ]
Wu, Xinzhou [1 ]
Tang, Cheng [1 ]
Chen, Minzhi [1 ]
Shi, Xiaoliu [2 ]
Liang, Songping [1 ]
Liu, Zhonghua [1 ]
机构：
[1] Hunan Normal Univ, Coll Life Sci, Natl &Local Joint Engn Lab Anim Peptide Drug Dev, Changsha 410081, Hunan, Peoples R China
[2] Cent South Univ, Xiangya Hosp 2, Dept Med Genet, Lab Clin Diag & Res, Changsha 41011, Peoples R China
来源：
TOXICON | 2019年 / 158卷
关键词：
Nav1.9; Gain-of-function mutation; Pain disorders;
D O I：
10.1016/j.toxicon.2018.10.196
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
187
引用
收藏
页码：S57 / S57
页数：1
相关论文
共 50 条
  • [1] Electrophysiological and Pharmacological Analyses of Nav1.9 Voltage-Gated Sodium Channel by Establishing a Heterologous Expression System
    Zhou, Xi
    Xiao, Zhen
    Xu, Yan
    Zhang, Yunxiao
    Tang, Dongfang
    Wu, Xinzhou
    Tang, Cheng
    Chen, Minzhi
    Shi, Xiaoliu
    Chen, Ping
    Liang, Songping
    Liu, Zhonghua
    FRONTIERS IN PHARMACOLOGY, 2017, 8
  • [2] The voltage-gated sodium channel NaV1.9 in visceral pain
    Hockley, J. R. F.
    Winchester, W. J.
    Bulmer, D. C.
    NEUROGASTROENTEROLOGY AND MOTILITY, 2016, 28 (03): : 316 - 326
  • [3] Nav1.9: A unique voltage-gated sodium channel with a role in inflammatory pain
    Theys, Margaux
    Bosmans, Frank
    BIOPHYSICAL JOURNAL, 2023, 122 (03) : 103A - 103A
  • [4] The voltage-gated sodium channel Nav1.9 is an effector of peripheral inflammatory pain hypersensitivity
    Amaya, Fumimasa
    Wang, Haibin
    Costigan, Michael
    Allchorne, Andrew J.
    Hatcher, Jon P.
    Egerton, Julie
    Stean, Tania
    Morisset, Valerie
    Grose, David
    Gunthorpe, Martin J.
    Chessell, Iain P.
    Tate, Simon
    Green, Paula J.
    Woolf, Clifford J.
    JOURNAL OF NEUROSCIENCE, 2006, 26 (50): : 12852 - 12860
  • [5] Voltage-gated sodium channel mutations and painful neuropathy: Nav1.9 joins the family
    Bennett, David L. H.
    BRAIN, 2014, 137 : 1574 - 1576
  • [6] NaV1.9: a sodium channel linked to human pain
    Sulayman D. Dib-Hajj
    Joel A. Black
    Stephen G. Waxman
    Nature Reviews Neuroscience, 2015, 16 : 511 - 519
  • [7] The voltage-gated sodium channel Nav1.9 is required for inflammation-based urinary bladder dysfunction
    Ritter, Amy M.
    Martin, William J.
    Thorneloe, Kevin S.
    NEUROSCIENCE LETTERS, 2009, 452 (01) : 28 - 32
  • [8] Contribution of the tetrodotoxin-resistant voltage-gated sodium channel Nav1.9 to sensory transmission and nociceptive behavior
    Priest, BT
    Murphy, BA
    Lindia, JA
    Diaz, C
    Abbadie, C
    Ritter, AM
    Liberator, P
    Iyer, LM
    Kash, SF
    Kohler, MG
    Kaczorowski, GJ
    MacIntyre, DE
    Martin, WJ
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (26) : 9382 - 9387
  • [9] Direct interaction with contactin targets voltage-gated sodium channel Nav1.9/NaN to the cell membrane.
    Liu, CJ
    Dib-Hajj, SD
    Black, JA
    Greenwood, J
    Lian, Z
    Waxman, SG
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (49) : 46553 - 46561
  • [10] Tetrodotoxin-resistant voltage-gated sodium channels Nav1.8 and Nav1.9 are expressed in the retina
    O'Brien, Brendan J.
    Caldwell, John H.
    Ehring, George R.
    O'Brien, Keely M. Bumsted
    Luo, Songjiang
    Levinson, S. Rock
    JOURNAL OF COMPARATIVE NEUROLOGY, 2008, 508 (06) : 940 - 951
12345