Dissecting the effects of cooperativity on the stabilisation of a de novo designed three stranded anti-parallel beta-sheet

被引：0

作者：

Sharman, GJ ^{[1
]}

Searle, MS ^{[1
]}

机构：

[1] UNIV NOTTINGHAM,DEPT CHEM,NOTTINGHAM NG7 2RD,ENGLAND

来源：

CHEMICAL COMMUNICATIONS | 1997年 / 20期

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Cooperative effects between two sets of weak interactions at different hydrogen bonded interfaces are shown to stabilise a de novo designed three-stranded anti-parallel beta-sheet: NMR and CD (circular dichroism) spectroscopy have been used to compare and contrast the stability of the beta-sheet (residues 1-24) and the isolated C-terminal beta-hairpin (residues 9-24).

引用

页码：1955 / 1956

页数：2

共 13 条

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