2-hydroxybenzoic acid salt of physostigmine

被引：1

作者：

Flippen-Anderson, JL

Deschamps, JR

Brossi, A

Greig, NH

机构：

[1] USN, Res Lab, Struct Matter Lab, Washington, DC 20375 USA

[2] Univ N Carolina, Sch Pharm, Chapel Hill, NC 27599 USA

[3] NIA, Drug Design & Dev Sect, Neurosci Lab, Gerontol Res Ctr 4E02,NIH, Baltimore, MD 21224 USA

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2002年 / 58卷

关键词：

D O I：

10.1107/S1600536802012278

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

Physostigmine, C15H22N3O2, is the major alkaloid found in the seeds of Calabar beans. It was the first anticholinesterase used in the treatment of Alzheimer's disease and is still used in the treatment of glaucoma. The structure of its 2-hydroxybenzoate salt, viz. 5-carbamoyloxy-1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-1-ium benzoate, C15H22N3O2+.C7H5O3-, is reported.

引用

页码：o853 / o855

页数：3

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