Task-induced deactivation in diverse brain systems correlates with interindividual differences in distinct autonomic indices

被引:5
|
作者
Iacovella, Vittorio [1 ]
Faes, Luca [2 ,3 ]
Hasson, Uri [1 ,4 ]
机构
[1] Univ Trento, Ctr Mind Brain Sci, Trento, Italy
[2] Univ Trento, BIOtech, Dept Ind Engn, Trento, Italy
[3] IRCS PAT FBK Trento, Trento, Italy
[4] Univ Chicago, Ctr Pract Wisdom, Chicago, IL 60637 USA
基金
欧洲研究理事会;
关键词
ANS; Deactivation; Arithmetic; Interindividual differences; HEART-RATE-VARIABILITY; MEDIAL PREFRONTAL CORTEX; DEFAULT-MODE NETWORK; NERVOUS-SYSTEM; CINGULATE CORTEX; MENTAL STRESS; INDIVIDUAL-DIFFERENCES; NEURAL RESPONSES; VAGAL TONE; EEG-THETA;
D O I
10.1016/j.neuropsychologia.2018.03.005
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Neuroimaging research has shown that different cognitive tasks induce relatively specific activation patterns, as well as less task-specific deactivation patterns. Here we examined whether individual differences in Autonomic Nervous System (ANS) activity during task performance correlate with the magnitude of task-induced deactivation. In an fMRI study, participants performed a continuous mental arithmetic task in a task/rest block design, while undergoing combined fMRI and heart/respiration rate acquisitions using photoplethysmograph and respiration belt. As expected, task performance increased heart-rate and reduced the RMSSD, a cardiac index related to vagal tone. Across participants, higher heart rate during task was linked to increased activation in fronto-parietal regions, as well as to stronger deactivation in ventromedial prefrontal regions. Respiration frequency during task was associated with similar patterns, but in different regions than those identified for heart rate. Finally, in a large set of regions, almost exclusively limited to the Default Mode Network, lower RMSSD was associated with greater deactivation, and furthermore, the vast majority of these regions were task-deactivated at the group level. Together, our findings show that inter-individual differences in ANS activity are strongly linked to task-induced deactivation. Importantly, our findings suggest that deactivation is a multifaceted construct potentially linked to ANS control, because distinct ANS measures correlate with deactivation in different regions. We discuss the implications for current theories of cortical control of the ANS and for accounts of deactivation, with particular reference to studies documenting a "failure to deactivate" in multiple clinical states.
引用
收藏
页码:29 / 42
页数:14
相关论文
共 11 条
  • [1] Task-induced deactivation correlates with suspension of task-unrelated thoughts: An fMRI investigation
    McKiernan, K
    D'Angelo, B
    Kucera-Thompson, JK
    Kaufman, J
    Binder, J
    [J]. JOURNAL OF COGNITIVE NEUROSCIENCE, 2002, : 96 - 96
  • [2] Developmental Changes in Task-Induced Brain Deactivation in Humans Revealed by a Motor Task
    Morita, Tomoyo
    Asada, Minoru
    Naito, Eiichi
    [J]. DEVELOPMENTAL NEUROBIOLOGY, 2019, 79 (06) : 536 - 558
  • [3] Task-Induced Deactivation from Rest Extends beyond the Default Mode Brain Network
    Harrison, Ben J.
    Pujol, Jesus
    Contreras-Rodriguez, Oren
    Soriano-Mas, Carles
    Lopez-Sola, Marina
    Deus, Joan
    Ortiz, Hector
    Blanco-Hinojo, Laura
    Alonso, Pino
    Hernandez-Ribas, Rosa
    Cardoner, Narcis
    Menchon, Jose M.
    [J]. PLOS ONE, 2011, 6 (07):
  • [4] Default-mode function and task-induced deactivation have overlapping brain substrates in children
    Thomason, Moriah E.
    Chang, Catherine E.
    Glover, Gary H.
    Gabrieli, John D. E.
    Greicius, Michael D.
    Gotlib, Ian H.
    [J]. NEUROIMAGE, 2008, 41 (04) : 1493 - 1503
  • [5] Task-induced brain connectivity promotes the detection of individual differences in brain-behavior relationships
    Jiang, Rongtao
    Zuo, Nianming
    Ford, Judith M.
    Qi, Shile
    Zhi, Dongmei
    Zhuo, Chuanjun
    Xu, Yong
    Fu, Zening
    Bustillo, Juan
    Turner, Jessica A.
    Calhoun, Vince D.
    Sui, Jing
    [J]. NEUROIMAGE, 2020, 207
  • [6] Magnitude of Task-induced Deactivation of Insula and Anterior Cingulate Cortex is related to Inter-individual Differences in RMSSD
    Iacovella, Vittorio
    Hasson, Uri
    [J]. 2014 8TH CONFERENCE OF THE EUROPEAN STUDY GROUP ON CARDIOVASCULAR OSCILLATIONS (ESGCO), 2014, : 153 - +
  • [7] Prospective evaluation of functional brain activity and oxidative damage in breast cancer: changes in task-induced deactivation during a working memory task
    Root, James C.
    Pergolizzi, Denise
    Pan, Hong
    Orlow, Irene
    Passik, Steven D.
    Silbersweig, David
    Stern, Emily
    Ahles, Tim A.
    [J]. BRAIN IMAGING AND BEHAVIOR, 2021, 15 (03) : 1364 - 1373
  • [8] Functional imaging evidence for task-induced deactivation and disconnection of a major default mode network hub in the mouse brain
    Ferrier, Jeremy
    Tiran, Elodie
    Deffieux, Thomas
    Tanter, Mickael
    Lenkei, Zsolt
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (26) : 15270 - 15280
  • [9] Prospective evaluation of functional brain activity and oxidative damage in breast cancer: changes in task-induced deactivation during a working memory task
    James C. Root
    Denise Pergolizzi
    Hong Pan
    Irene Orlow
    Steven D. Passik
    David Silbersweig
    Emily Stern
    Tim A. Ahles
    [J]. Brain Imaging and Behavior, 2021, 15 : 1364 - 1373
  • [10] Subclinical Cognitive Decline in Middle-Age is Associated With Reduced Task-induced Deactivation of the Brain's Default Mode Network
    Hansen, Naja Liv
    Lauritzen, Martin
    Mortensen, Erik Lykke
    Osler, Merete
    Avlund, Kirsten
    Fagerlund, Birgitte
    Rostrup, Egill
    [J]. HUMAN BRAIN MAPPING, 2014, 35 (09) : 4488 - 4498