The effect of topically administered lavender aromatherapy on the pain of insulin injection in diabetic patients: a double-blind randomized controlled clinical trial
Background/aim: Needle phobia occurs in more than half of diabetic patients due to the pain caused by frequent insulin injections. Therefore, this study evaluated the effect of topically administered lavender aromatherapy on the pain of insulin injections in diabetic patients. Materials and methods: In this double-blind randomized controlled and experimental study, patients who met the study criteria were divided into three groups; topical lavender oil (n = 60), placebo (n = 60), and control (n = 60) groups. The data were collected using the "Patient Information Form", the "Follow-up Form", the "Verbal Category Scale (VCS)", and the "Visual Analogue Scale (VAS)". Results: The results revealed no significant difference between the patients in the topical lavender oil group before and during the insulin injection in terms of VAS and VCS pain scores (p > 0.05). In the placebo and control groups, the mean VAS and VCS pain scores during insulin injection were found to be significantly higher than before insulin injection (p < 0.05). Besides, the mean VAS and VCS scores during insulin injection were significantly higher in the placebo and control groups than the topical lavender oil group (p < 0.05). Conclusion: The study showed that patients who were administered topical lavender oil felt less pain after insulin injection than those in the placebo and control groups. Therefore, topically applied lavender aromatherapy can be easily used for pain control in insulin-dependent diabetic patients (clinical trial number NCT04767737).
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Kerman Univ Med Sci, Inst Neuropharmacol, Neurosci Res Ctr, Kerman, Iran
Kerman Univ Med Sci, Fac Persian Med, Dept Tradit Med, Kerman, IranKerman Univ Med Sci, Inst Neuropharmacol, Neurosci Res Ctr, Kerman, Iran
Motaghi, Najmeh
Tajadini, Haleh
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Kerman Univ Med Sci, Neurol Res Ctr, Kerman, Iran
Kerman Univ Med Sci, Fac Persian Med, Dept Tradit Med, Kerman, IranKerman Univ Med Sci, Inst Neuropharmacol, Neurosci Res Ctr, Kerman, Iran
Tajadini, Haleh
Shafiei, Kaveh
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Kerman Univ Med Sci, Neurol Res Ctr, Kerman, IranKerman Univ Med Sci, Inst Neuropharmacol, Neurosci Res Ctr, Kerman, Iran
Shafiei, Kaveh
Sharififar, Fariba
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Kerman Univ Med Sci, Fac Pharm, Herbal & tradit Med Res Ctr, Kerman, IranKerman Univ Med Sci, Inst Neuropharmacol, Neurosci Res Ctr, Kerman, Iran
Sharififar, Fariba
Ansari, Mehdi
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Kerman Univ Med Sci, Fac Pharm, Dept Drug & Food Control, Kerman, IranKerman Univ Med Sci, Inst Neuropharmacol, Neurosci Res Ctr, Kerman, Iran
Ansari, Mehdi
Sharifi, Hamid
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Kerman Univ Med Sci, HIV STI Surveillance Res Ctr, Kerman, Iran
Kerman Univ Med Sci, Inst Futures Studies Hlth, WHO Collaborating Ctr HIV Surveillance, Kerman, IranKerman Univ Med Sci, Inst Neuropharmacol, Neurosci Res Ctr, Kerman, Iran
Sharifi, Hamid
Sarhadynejad, Zarrin
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Kerman Univ Med Sci, Fac Pharm, Herbal & tradit Med Res Ctr, Kerman, Iran
Kerman Univ Med Sci, Fac Persian Med, Dept Pharm Med, Kerman, IranKerman Univ Med Sci, Inst Neuropharmacol, Neurosci Res Ctr, Kerman, Iran
Sarhadynejad, Zarrin
Tavakoli-Far, Fateme
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Islamic Azad Univ, Fac Pharm, Ayatollah Amoli Branch, Amol, Iran
Shiraz Univ Med Sci, Sci Assoc Indigenous Knowledge, Shiraz, IranKerman Univ Med Sci, Inst Neuropharmacol, Neurosci Res Ctr, Kerman, Iran
Tavakoli-Far, Fateme
Kamali, Hoda
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Kerman Univ Med Sci, Neurol Res Ctr, Kerman, IranKerman Univ Med Sci, Inst Neuropharmacol, Neurosci Res Ctr, Kerman, Iran
Kamali, Hoda
Amiri-Ardekani, Ehsan
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Shiraz Univ Med Sci, Fac Pharm, Dept Phytopharmaceut Tradit Pharm, Shiraz, Iran
Shiraz Univ Med Sci, Student Res Comm, Shiraz, IranKerman Univ Med Sci, Inst Neuropharmacol, Neurosci Res Ctr, Kerman, Iran