Contact Lens-induced Limbal Stem Cell Deficiency

被引:48
|
作者
Rossen, Jennifer [1 ]
Amram, Alec [1 ]
Milani, Behrad [1 ]
Park, Dongwook [1 ]
Harthan, Jennifer [2 ]
Joslin, Charlotte [1 ]
McMahon, Timothy [1 ]
Djalilian, Ali [1 ]
机构
[1] Univ Chicago, Dept Ophthalmol & Visual Sci, Chicago, IL 60637 USA
[2] Illinois Eye Inst, Illinois Coll Optometry, Chicago, IL USA
来源
OCULAR SURFACE | 2016年 / 14卷 / 04期
关键词
corneal conjunctivalization; contact lens; limbal stem cell deficiency; limbal stem cells; AMNIOTIC MEMBRANE TRANSPLANTATION; EPITHELIAL TRANSPLANTATION; SURFACE RECONSTRUCTION; CLINICAL-FEATURES; DRY EYE; KERATOCONJUNCTIVITIS; MANAGEMENT; WEAR; DIFFERENTIATION; EXPRESSION;
D O I
10.1016/j.jtos.2016.06.003
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Limbal stem cell deficiency (LSCD) is a pathologic condition caused by the dysfunction and/or destruction of stem cell precursors of the corneal epithelium, typified clinically by corneal conjunctivalization. The purpose of this review is to critically discuss a less well-known cause of limbal stem cell disease: contact lens (CL) wear. A literature search was conducted to include original articles containing patients with CL-induced LSCD. This review describes epidemiology, diagnostic strategies, pathogenesis, differential diagnosis, and treatment modalities for this condition.
引用
收藏
页码:419 / 434
页数:16
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