Prognostic significance of parameters of heart rate variability as a risk factor of development of hypertension

Risk factors and parameters of heart rate variability during active orthoclinostatic test in subjects with normal blood pressure were assessed in a 5 year cohort study on 519 individuals. Logistic stepwise regression revealed most informative factors associated with development of hypertension: sex (p=0.029), body mass index (p=0.005), salt sensitivity threshold (p=0.048), dynamics of heart rate during exercise test (p=0.035). Addition of parameters of heart rate variability (dynamics of standard deviation of R-R intervals and of low frequency component of spectrum during active orthoclinostatic test) increased accuracy of prognosis. With the use of constructed models risk profiles were calculated. Thus, parameters of heart rate variability allow to improve prognostic value of a model.