Structural, Raman and optical characteristics of Sn doped CuO nanostructures: A novel anticancer agent

被引:34
|
作者
Jan, Tariq [1 ]
Iqbal, J. [1 ,6 ,7 ]
Farooq, Umar [1 ]
Gul, Asma [2 ,3 ]
Abbasi, Rashda [4 ]
Ahmad, Ishaq [5 ,6 ,7 ]
Malik, Maaza [5 ,6 ]
机构
[1] Int Islamic Univ, Dept Phys, Lab Nanosci & Technol, Islamabad, Pakistan
[2] Int Islamic Univ, Dept Bioinfonnat, Islamabad, Pakistan
[3] Int Islamic Univ, Dept Biotechnol, Islamabad, Pakistan
[4] IBGE, Islamabad, Pakistan
[5] Natl Ctr Phys, Expt Phys Labs, Islamabad 44000, Pakistan
[6] Univ S Africa, Coll Grad Studies, UNESCO UNISA Africa Chair Nanosci Nanotechnol, ZA-0001 Pretoria, South Africa
[7] iThemba LABS Nat Res Fdn, Nanosci African Network NANOAFNET, Somerset West, Western Cape Pr, South Africa
关键词
Optical properties; Sn doped CuO; Raman spectroscopy; Anticancer activity; COPPER; NANOPARTICLES; NANOWIRES; NANORODS;
D O I
10.1016/j.ceramint.2015.06.080
中图分类号
TQ174 [陶瓷工业]; TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
SnxCu1-xO (where x=0, 0.04, 0.06 & 0.10) nanostructures have been prepared via co-precipitation technique and characterized for different physiochemical properties and anticancer activity. The synthesized nanostructures exhibit single phase monoclinic structure of CuO as confirmed by x-ray diffraction (XRD), Raman and Fourier transform infrared (FTIR) spectroscopy results. The Sn ions doping into CuO has been found to tailor the structural and morphological properties. The UV-visible absorption spectra show that CuO nanostructures have wide absorption peak extended from UV to visible region which is strongly influenced by the introduction of Sn ions in the host matrix. Finally, anticancer activity of the synthesized nanostructures has been determined against HeLa cancer cell line. Undoped CuO exhibits a stronger anticancer activity as compared to Sn doped CuO nanostructures which has been linked with the optical properties of these nanostructures. (C) 2015 Elsevier Ltd and Techna Group S.r.l. All rights reserved.
引用
收藏
页码:13074 / 13079
页数:6
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