Early diagnosis of Parkinson's disease

被引:11
|
作者
Spiegel, Joerg
Storch, Alexander
Jost, Wolfgang H.
机构
[1] Univ Saarland, Dept Neurol, D-66421 Homburg, Germany
[2] Tech Univ Dresden, Dept Neurol, D-01307 Dresden, Germany
[3] Deutsch Klin Diagnost, Dept Neurol, D-65191 Wiesbaden, Germany
关键词
Parkinson's disease; olfactory dysfunction; transcranial ultrasound; FP-CIT SPECT; MIBG scintigraphy;
D O I
10.1007/s00415-006-4002-6
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The clinical methods of olfactory testing and color discrimination as well as apparative methods such as transcranial ultrasound, dopamine transporter imaging and MIBG scintigraphy reveal a high sensitivity concerning the diagnosis of idiopathic Parkinson's disease (PD). The specificity of the presented methods, in particular of the dopamine transporter imaging seems to be limited. All these methods and primarily their combination allow the detection of PD in early and - probably - preclinical stages. This requires sufficient therapeutic strategies to prevent and treat preclinical and early PD.
引用
收藏
页码:2 / 7
页数:6
相关论文
共 50 条
  • [1] The early diagnosis of Parkinson's disease
    Brooks, DJ
    [J]. ANNALS OF NEUROLOGY, 1998, 44 (03) : S10 - S18
  • [2] Early diagnosis in Parkinson's disease
    Juri Claveria, Carlos Andres
    Uribe San Martin, Reinaldo
    [J]. SALUD I CIENCIA, 2009, 16 (08): : 839 - 844
  • [3] EARLY DIAGNOSIS OF PARKINSON'S DISEASE
    Gaenslen, Alexandra
    Berg, Daniela
    [J]. TRANSCRANIAL SONOGRAPHY IN MOVEMENT DISORDERS, 2010, 90 : 81 - 92
  • [4] Early diagnosis of Parkinson's disease
    Georg Becker
    Antje Müller
    Stefan Braune
    Thomas Büttner
    Reiner Benecke
    Wolfgang Greulich
    Wolfgang Klein
    Günter Mark
    Jürgen Rieke
    Reiner Thümler
    [J]. Journal of Neurology, 2002, 249 (Suppl 3) : iii40 - iii48
  • [5] Early diagnosis of Parkinson’s disease
    Jörg Spiegel
    Alexander Storch
    Wolfgang H. Jost
    [J]. Journal of Neurology, 2006, 253 : iv2 - iv7
  • [6] Issues in the early diagnosis of Parkinson's disease
    Koller, WC
    Montgomery, EB
    [J]. NEUROLOGY, 1997, 49 (01) : S10 - S25
  • [7] Accuracy of the Early Diagnosis of Parkinson's Disease
    Beach, Thomas G.
    Adler, Charles H.
    Shill, Holly A.
    Zhang, Nan
    Driver-Dunckley, Erika D.
    Mehta, Shyamal H.
    Serrano, Geidy E.
    [J]. MOVEMENT DISORDERS, 2023, 38 (08) : 1573 - 1574
  • [8] Approaches to the Early Diagnosis of Parkinson’s Disease
    Katunina E.A.
    Ilina E.P.
    Sadekhova G.I.
    Gaisenuk E.I.
    [J]. Neuroscience and Behavioral Physiology, 2020, 50 (4) : 393 - 400
  • [9] Methods for the early diagnosis of Parkinson's disease
    Becker, G
    [J]. NERVENARZT, 2003, 74 (Suppl 1): : S7 - S11
  • [10] Research progress in the early diagnosis of Parkinson’s disease
    LinLin Xie
    LuDong Hu
    [J]. Neurological Sciences, 2022, 43 : 6225 - 6231