Molecular detection and phylogenetic analysis of human parechovirus in children with acute gastroenteritis in Iran

被引:0
|
作者
Mohammadi, Mehrdad [1 ]
Armin, Shahnaz [2 ]
Piroozmand, Ahmad [3 ,4 ]
机构
[1] Kashan Univ Med Sci, Sch Med, Dept Microbiol & Immunol, Med Bacteriol, Kashan, Iran
[2] Shaheed Behesti Univ Med Sci, Fac Med, Pediat Infect Res Ctr, Pediat Infect Dis, Tehran, Iran
[3] Kashan Univ Med Sci, Sch Med, Dept Microbiol & Immunol, Med Virol, Kashan, Iran
[4] Kashan Univ Med Sci, Autoimmune Dis Res Ctr, Sch Med, Kasha, Iran
关键词
acute gastroenteritis; direct genotyping; human parechovirus; Iran; STOOL SAMPLES; HOSPITALIZED CHILDREN; VIRAL GASTROENTERITIS; GENETIC DIVERSITY; HUMAN BOCAVIRUS; AICHI VIRUS; EPIDEMIOLOGY; ENTEROVIRUSES; PREVALENCE; INFECTION;
D O I
10.2217/fvl-2020-0114
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Aim: Human parechovirus (HPeV) is one of the major causes of acute gastroenteritis in children. Materials & methods: Stool specimens (n = 250) were collected from children aged <= 3 years during 2018-2019. HPeV RNA was detected by reverse transcription-PCR and genotyping by VP1 gene, Rotavirus (RV) screened by ELISA. Results: HPeV was detected in 12% of the cases. The children under 6-months old (64.2%) were a sensitive group and HPeV was more prevalent during January-February (73.3%). The co-infection of HPeV with RV was 50%. All of the sequenced samples belong to the HPeV-1 genotype. Conclusion: HPeV-1 is one of the major causes of acute viral gastroenteritis in children and the co-infection of RV can be an additional infection in some cases.
引用
收藏
页码:783 / 789
页数:8
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