Genotyping of immune-related genetic variants identifies TYK2 as a novel associated locus for idiopathic inflammatory myopathies

被引：27

作者：

Jani, M. ^{[1
]}

Massey, J. ^{[1
,2
]}

Wedderburn, L. R. ^{[3
]}

Vencovsky, J. ^{[4
]}

Danko, K. ^{[5
]}

Lundberg, I. E. ^{[6
]}

Padyukov, L. ^{[6
]}

Selva-O'Callaghan, A. ^{[7
]}

Radstake, T. ^{[8
]}

Platt, H. ^{[9
]}

Warren, R. B. ^{[2
]}

Griffiths, C. E. ^{[2
]}

Lee, A. ^{[10
]}

Gregersen, P. K. ^{[10
]}

Miller, F. W. ^{[11
]}

Ollier, W. E. ^{[9
]}

Cooper, R. G. ^{[12
]}

Chinoy, H. ^{[1
,9
]}

Lamb, J. A. ^{[9
]}

机构：

[1] Univ Manchester, Manchester Acad Hlth Sci Ctr, Arthrit Res UK Ctr Epidemiol, Ctr Musculoskeletal Res, Manchester M13 9PT, Lancs, England

[2] Univ Manchester, Manchester Acad Hlth Sci Ctr, Salford Royal NHS Fdn Trust, Dermatol Ctr, Manchester M13 9PT, Lancs, England

[3] UCL, Inst Child Hlth, Rheumatol Unit, London, England

[4] Charles Univ Prague, Inst Rheumatol, Prague, Czech Republic

[5] Univ Debrecen, H-4012 Debrecen, Hungary

[6] Karolinska Univ Hosp, Karolinska Inst, Dept Med, Rheumatol Unit, Stockholm, Sweden

[7] Vall dHebron Gen Hosp, Barcelona, Spain

[8] Univ Med Ctr Utrecht, Lab Translat Immunol, Utrecht, Netherlands

[9] Univ Manchester, Manchester Acad Hlth Sci Ctr, Ctr Integrated Genom Med Res, Manchester M13 9PT, Lancs, England

[10] Feinstein Inst Med Res, Manhasset, NY USA

[11] NIEHS, NIH, Bethesda, MD USA

[12] Univ Liverpool, Dept Musculoskeletal Biol, Liverpool L69 3BX, Merseyside, England

来源：

ANNALS OF THE RHEUMATIC DISEASES | 2014年 / 73卷 / 09期

基金：

英国医学研究理事会; 英国惠康基金;

关键词：

SUSCEPTIBILITY LOCI; DERMATOMYOSITIS; POLYMYOSITIS; ARTHRITIS;

D O I：

10.1136/annrheumdis-2014-205440

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1750 / 1752

页数：3

共 27 条

[1] Dense genotyping of immune-related loci identifies HLA variants associated with increased risk of collagenous colitis
Westerlind, Helga
Mellander, Marie-Rose
Bresso, Francesca
Munch, Andreas
Bonfiglio, Ferdinando
Assadi, Ghazaleh
Rafter, Joseph
Huebenthal, Matthias
Lieb, Wolfgang
Kallberg, Henrik
Brynedal, Boel
Padyukov, Leonid
Halfvarson, Jonas
Torkvist, Leif
Bjork, Jan
Andreasson, Anna
Agreus, Lars
Almer, Sven
Miehlke, Stephan
Madisch, Ahmed
Ohlsson, Bodil
Lofberg, Robert
Hultcrantz, Rolf
Franke, Andre
D'Amato, Mauro
GUT, 2017, 66 (03) : 421 - 428
[2] IMMUNOCYTOCHEMICAL AND HISTOCYTOCHEMICAL CHARACTERIZATION OF LOCAL IMMUNE-RELATED CELLS IN IDIOPATHIC INFLAMMATORY MYOPATHIES
BODENSTEINER, JB
FEEBACK, D
ANNALS OF NEUROLOGY, 1983, 14 (03) : 373 - 374
[3] Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups
Rothwell, Simon
Cooper, Robert G.
Lundberg, Ingrid E.
Miller, Frederick W.
Gregersen, Peter K.
Bowes, John
Vencovsky, Jiri
Danko, Katalin
Limaye, Vidya
Selva-O'Callaghan, Albert
Hanna, Michael G.
Machado, Pedro M.
Pachman, Lauren M.
Reed, Ann M.
Rider, Lisa G.
Cobb, Joanna
Platt, Hazel
Molberg, Oyvind
Benveniste, Olivier
Mathiesen, Pernille
Radstake, Timothy
Doria, Andrea
De Bleecker, Jan
De Paepe, Boel
Maurer, Britta
Ollier, William E.
Padyukov, Leonid
O'Hanlon, Terrance P.
Lee, Annette
Amos, Christopher I.
Gieger, Christian
Meitinger, Thomas
Winkelmann, Juliane
Wedderburn, Lucy R.
Chinoy, Hector
Lamb, Janine A.
ANNALS OF THE RHEUMATIC DISEASES, 2016, 75 (08) : 1558 - 1566
[4] Targeted capture sequencing identifies novel genetic variations in Chinese patients with idiopathic inflammatory myopathies
Peng, Qing-Lin
Lin, Jin-Ming
Zhang, Yong-Biao
Zhang, Xue-Zhi
Wang, Pan-Pan
Wu, Ting-Ting
Yu, Jun
Dong, Xiao-Qun
Gu, Ming-Liang
Wang, Guo-Chun
INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, 2018, 21 (08) : 1619 - 1626
[5] Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis
Hinks, Anne
Cobb, Joanna
Marion, Miranda C.
Prahalad, Sampath
Sudman, Marc
Bowes, John
Martin, Paul
Comeau, Mary E.
Sajuthi, Satria
Andrews, Robert
Brown, Milton
Chen, Wei-Min
Concannon, Patrick
Deloukas, Panos
Edkins, Sarah
Eyre, Stephen
Gaffney, Patrick M.
Guthery, Stephen L.
Guthridge, Joel M.
Hunt, Sarah E.
James, Judith A.
Keddache, Mehdi
Moser, Kathy L.
Nigrovic, Peter A.
Onengut-Gumuscu, Suna
Onslow, Mitchell L.
Rose, Carlos D.
Rich, Stephen S.
Steel, Kathryn J. A.
Wakeland, Edward K.
Wallace, Carol A.
Wedderburn, Lucy R.
Woo, Patricia
Bohnsack, John F.
Haas, Johannes Peter
Glass, David N.
Langefeld, Carl D.
Thomson, Wendy
Thompson, Susan D.
NATURE GENETICS, 2013, 45 (06) : 664 - +
[6] Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis
Anne Hinks
Joanna Cobb
Miranda C Marion
Sampath Prahalad
Marc Sudman
John Bowes
Paul Martin
Mary E Comeau
Satria Sajuthi
Robert Andrews
Milton Brown
Wei-Min Chen
Patrick Concannon
Panos Deloukas
Sarah Edkins
Stephen Eyre
Patrick M Gaffney
Stephen L Guthery
Joel M Guthridge
Sarah E Hunt
Judith A James
Mehdi Keddache
Kathy L Moser
Peter A Nigrovic
Suna Onengut-Gumuscu
Mitchell L Onslow
Carlos D Rosé
Stephen S Rich
Kathryn J A Steel
Edward K Wakeland
Carol A Wallace
Lucy R Wedderburn
Patricia Woo
John F Bohnsack
Johannes Peter Haas
David N Glass
Carl D Langefeld
Wendy Thomson
Susan D Thompson
Nature Genetics, 2013, 45 : 664 - 669
[7] High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry
Sun, Celi
Molineros, Julio E.
Looger, Loren L.
Zhou, Xu-jie
Kim, Kwangwoo
Okada, Yukinori
Ma, Jianyang
Qi, Yuan-yuan
Kim-Howard, Xana
Motghare, Prasenjeet
Bhattarai, Krishna
Adler, Adam
Bang, So-Young
Lee, Hye-Soon
Kim, Tae-Hwan
Kang, Young Mo
Suh, Chang-Hee
Chung, Won Tae
Park, Yong-Beom
Choe, Jung-Yoon
Shim, Seung Cheol
Kochi, Yuta
Suzuki, Akari
Kubo, Michiaki
Sumida, Takayuki
Yamamoto, Kazuhiko
Lee, Shin-Seok
Kim, Young Jin
Han, Bok-Ghee
Dozmorov, Mikhail
Kaufman, Kenneth M.
Wren, Jonathan D.
Harley, John B.
Shen, Nan
Chua, Kek Heng
Zhang, Hong
Bae, Sang-Cheol
Nath, Swapan K.
NATURE GENETICS, 2016, 48 (03) : 323 - 330
[8] High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry
Celi Sun
Julio E Molineros
Loren L Looger
Xu-jie Zhou
Kwangwoo Kim
Yukinori Okada
Jianyang Ma
Yuan-yuan Qi
Xana Kim-Howard
Prasenjeet Motghare
Krishna Bhattarai
Adam Adler
So-Young Bang
Hye-Soon Lee
Tae-Hwan Kim
Young Mo Kang
Chang-Hee Suh
Won Tae Chung
Yong-Beom Park
Jung-Yoon Choe
Seung Cheol Shim
Yuta Kochi
Akari Suzuki
Michiaki Kubo
Takayuki Sumida
Kazuhiko Yamamoto
Shin-Seok Lee
Young Jin Kim
Bok-Ghee Han
Mikhail Dozmorov
Kenneth M Kaufman
Jonathan D Wren
John B Harley
Nan Shen
Kek Heng Chua
Hong Zhang
Sang-Cheol Bae
Swapan K Nath
Nature Genetics, 2016, 48 : 323 - 330
[9] Genetic association between the PTPN22, IRF5 and TYK2 gene variants and susceptibility to juvenile idiopathic arthritis
Qian, Yufeng
Chen, Bingqian
Wang, Zhengfei
Peng, Yuqin
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2022, 24 (06)
[10] Dense Genotyping of Immune-Related Loci Identifies Variants Associated with Clearance of HPV among HIV-Positive Women in the HIV Epidemiology Research Study (HERS)
Sudenga, Staci L.
Wiener, Howard W.
King, Caroline C.
Rompalo, Anne M.
Cu-Uvin, Susan
Klein, Robert S.
Shah, Keerti V.
Sobel, Jack D.
Jamieson, Denise J.
Shrestha, Sadeep
PLOS ONE, 2014, 9 (06):

← 1 2 3 →