Non-canonical processes that shape the cell migration landscape

被引:12
|
作者
Majumdar, Ritankar [1 ]
Steen, Kaylee [2 ]
Coulombe, Pierre A. [2 ,3 ,4 ]
Parent, Carole A. [1 ,2 ,4 ]
机构
[1] Univ Michigan, Dept Pharmacol, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Dept Cell & Dev Biol, Ann Arbor, MI 48109 USA
[3] Univ Michigan, Dept Dermatol, Ann Arbor, MI 48109 USA
[4] Univ Michigan, Rogel Canc Ctr Michigan Med, Ann Arbor, MI 48109 USA
基金
美国国家卫生研究院;
关键词
VIMENTIN INTERMEDIATE-FILAMENTS; MITOCHONDRIA; EXOSOMES; NUCLEUS; TRANSPORT; TISSUE; REORGANIZATION; PROLIFERATION; TRANSCRIPTION; TRAFFICKING;
D O I
10.1016/j.ceb.2018.12.013
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Migration is a vital, intricate, and multi-faceted process that involves the entire cell, entails the integration of multiple external cues and, at times, necessitates high-level coordination among fields of cells that can be physically attached or not, depending on the physiological setting. Recent advances have highlighted the essential role of cellular components that have not been traditionally considered when studying cell migration. This review details how much we recently learned by studying the role of intermediate filaments, the nucleus, extracellular vesicles, and mitochondria during cell migration.
引用
收藏
页码:123 / 134
页数:12
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