Electroconvulsive therapy in Parkinson's disease

被引：15

作者：

Calderon-Fajardo, Humberto ^{[1
,2
]}

Cervantes-Arriaga, Amin ^{[1
]}

Llorens-Arenas, Rodrigo ^{[1
,2
]}

Ramirez-Bermudez, Jesus ^{[3
]}

Ruiz-Chow, Angel ^{[3
]}

Rodriguez-Violante, Mayela ^{[1
,2
]}

机构：

[1] Inst Nacl Neurol & Neurocirug, Lab Clin Enfermedades Neurodegenerat, Mexico City, DF, Mexico

[2] Inst Nacl Neurol & Neurocirug, Clin Trastornos Movimiento, Mexico City, DF, Mexico

[3] Inst Nacl Neurol & Neurocirug, Dept Neuropsiquiatria, Mexico City, DF, Mexico

来源：

ARQUIVOS DE NEURO-PSIQUIATRIA | 2015年 / 73卷 / 10期

关键词：

Parkinson's disease; electroconvulsive therapy; psychosis; depression; PLACEBO-CONTROLLED TRIAL; DOUBLE-BLIND; SYMPTOMS; DEPRESSION; PSYCHOSIS; ECT; STIMULATION; DISORDERS; STRATEGY; ANXIETY;

D O I：

10.1590/0004-282X20150131

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Objective: To analyze the effectiveness of electroconvulsive therapy for the management of depression and/or psychosis refractory to drug therapy in patients with Parkinson disease. Method:A retrospective study was carried out including patients treated with electroconvulsive therapy during the period between 2002 and 2013. A review of the literature was performed. Results: A total of 27 patients were included. In regards to the neuropsychiatric diagnosis, 14 patients had major depression, 12 patients had both psychosis and depression, and only one patient had isolated psychosis. The mean number of electroconvulsive therapy sessions was 12 +/- 2.8. After electroconvulsive therapy, all patients showed a statistically significant improvement in the Brief Psychiatric Rating scale (reduction of 52% points) and Hamilton Depression Rating Scale (reduction of 50% points) independent of the presence of psychosis, depression or both. Conclusion: Electroconvulsive therapy is effective for the treatment of refractory neuropsychiatric symptoms in Parkinson's disease.

引用

页码：856 / 860

页数：5

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