BPH: Why Do Patients Fail Medical Therapy?

被引：21

作者：

Gul, Zeynep G. ^{[1
]}

Kaplan, Steven A. ^{[1
]}

机构：

[1] Icahn Sch Med Mt Sinai, Dept Urol, 5 East 98th St,6th Floor, New York, NY 10029 USA

来源：

CURRENT UROLOGY REPORTS | 2019年 / 20卷 / 07期

关键词：

Benign prostatic hyperplasia; Medical therapy; Alpha-blockers; 5alpha-reductase inhibitors; Predictors of treatment failure; Clinical trial results; BENIGN PROSTATIC HYPERPLASIA; URINARY-TRACT SYMPTOMS; CLINICAL PROGRESSION; COMBINATION THERAPY; ERECTILE DYSFUNCTION; DEPRESSIVE SYMPTOMS; FINASTERIDE; MEN; EFFICACY; RISK;

D O I：

10.1007/s11934-019-0899-z

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Purpose of ReviewIn this article, we review why patients may fail medical therapy for benign prostatic hyperplasia (BPH) and by doing so, gain a better understanding of the disease process and how to optimize the care of these patients.Recent FindingsA growing body of literature has attempted to better characterize the various mechanisms by which patients develop BPH as well as identify predictors of disease progression and treatment failure.SummaryBPH is a heterogenous disease process. A more personalized approach to treatment, including patient selection for medical or surgical management, would allow us to optimize patient care.

引用

页数：7

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