Synthesis, structure and biological activities of novel triazole compounds containing N,N-dialkyldithlocarbamate moiety

The two compounds, 2,2-dimethyl-4-S-(N,N-dimethyldithiocarbamato)-5-(1,2,4-triazol-1-yl)-propione (1) and 2,2-dimethyl-4-S-(N,N-diethyldithiocarbamato)-5-(1,2,4-triazol-1-yl)-3-propione (2), were prepared by reacting N,N-dialkyldithiocarbamate sodium with 2,2-dimethyl-4-bromo-5-(1,2,4-triazol-1-yl)-propione. Their structures were identified by elemental analysis, IR and H-1 NMR spectroscopy. The structure of I has been determined by X-ray single crystal structure analysis. It crystallizes in monoclinic system with space group P2(1)/c, a = 1.2315(3) nm, b = 1.2057(2) nm, c = 1.2532(3) nm, beta = 118.55(3)degrees, Z = 4, V = 1.6345(6) nm(3), D-c = 1.221 g/cm(3), mu = 0.324 mm(-1), F(000) = 640, final R-1 = 0.0449. There is obvious potentially weak C-(HN)-N-... intermolecular interaction in the crystal, which stabilizes the crystal structure. The result of the biological test showed that the two compounds have fungistasis and plant growth regulating activities.