Normal skin biopsy as a tool for extra-cutaneous disorders

被引：3
|
作者：
Kluger, N. [1 ]
Fraitag, S. [2 ]
Roguedas, A. -M. [3 ]
Misery, L. [3 ]
机构：
[1] Univ Helsinki, Cent Hosp, Skin & Allergies Hosp, Dept Dermatol Venereol & Allergol, Helsinki 00029, Finland
[2] Hop Necker Enfants Malad, AP HP, Serv Anatomopathol, F-75015 Paris, France
[3] CHU, Serv Dermatol, F-29200 Brest, France
来源：
ANNALES DE DERMATOLOGIE ET DE VENEREOLOGIE | 2014年 / 141卷 / 03期
关键词：
Microscopy; Electronic microscopy; Amyloidosis; Alport syndrome; Sjogren's syndrome; CADASIL; Small-fiber neuropathy; Lysosomal storage disease; SALIVARY-GLAND BIOPSY; LAFORA-DISEASE; PERIPHERAL NEUROPATHY; SYSTEMIC AMYLOIDOSIS; DIAGNOSTIC-VALUE; ALPORTS-SYNDROME; COLLAGEN; CADASIL; COEXPRESSION; ASPIRATION;
D O I：
10.1016/j.annder.2014.01.005
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Biopsies of apparently healthy skin can contribute to the diagnosis of an internal disorder in a patient or in the detection of a potential disease carrier. Herein, we review those diseases for which dermatologists may be asked to perform a biopsy on normal skin where analysis by optical microscopy, immunofluorescence or electronic microscopy may result in diagnosis of an "internal'' disease. Diseases for which biopsies are required for cell cultures (e.g. fibroblasts cultures), clonality testing or chromosomal analysis are not discussed here. (C) 2014 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：192 / 200
页数：9
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