Syntheses and Configuration Determination of (+)-Villatamines A and B, Two Marine Natural Products

被引:6
|
作者
Hu, Lin [1 ,2 ]
Zhang, Lihe [1 ]
Zhai, Hongbin [1 ,2 ]
机构
[1] Peking Univ, State Key Lab Nat & Biomimet Drugs, Sch Pharmaceut Sci, Beijing 100083, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Synth Chem Nat Subst, Shanghai 200032, Peoples R China
来源
JOURNAL OF ORGANIC CHEMISTRY | 2009年 / 74卷 / 19期
关键词
INHIBITORS; ALKALOIDS; ALKYNES;
D O I
10.1021/jo901606r
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The first total syntheses of (+)-villatamines A and B have been realized in six and five steps, respectively. The stereogenic center present in these two naturally occurring alkaloids should have an (S)-configuration based on our results.
引用
收藏
页码:7552 / 7555
页数:4
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